Evidence map›Paper›PMID 38801100›Full record

ArticleCell proliferation2024

Combined lineage tracing and scRNA-seq reveal the activation of Sox9

Shang Chen, Yue Liu, Xiaoniao Chen, Hongyan Tao, Yongjun Piao, Haoyan Huang, Zhibo Han, Zhong-Chao Han, Xiang-Mei Chen, Zongjin Li

Abstract read
In one paragraph

Article in Cell proliferation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Prostaglandin EEXCLI journal · 2025
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shang ChenNankai University School of Medicine, Tianjin, China.
Yue LiuNankai University School of Medicine, Tianjin, China.
Xiaoniao ChenDepartment of Ophthalmology, The Third Medical Center of Chinese PLA General Hospital, Beijing, China.
Hongyan TaoMRC Molecular Hematology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK.
Yongjun PiaoNankai University School of Medicine, Tianjin, China.
Haoyan HuangNankai University School of Medicine, Tianjin, China.
Zhibo HanAcademy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China.
Zhong-Chao HanTianjin Key Laboratory of Engineering Technologies for Cell Pharmaceutical, National Engineering Research Center for Cell Products, AmCellGene Co., Ltd., Tianjin, China.
Xiang-Mei ChenNational Key Laboratory of Kidney Diseases, Chinese PLA General Hospital, Beijing, China.
Zongjin LiNankai University School of Medicine, Tianjin, China.ORCID https://orcid.org/0000-0002-4603-3743

Funding

Nankai University Eye Institute NKYKD202203National Key Research and Development Program of China 2017YFA0103200National Natural Science Foundation of China U2004126Natural Science Foundation of Tianjin Municipality 21JCZDJC00070Natural Science Foundation of Tianjin Municipality 22JCZXJC00170Tianjin Key Medical Discipline (Specialty) Construction Project TJYXZDXK-043A
6 · The paper itself

Abstract

Uncovering mechanisms of endogenous regeneration and repair through resident stem cell activation will allow us to develop specific therapies for injuries and diseases by targeting resident stem cell lineages. Sox9

Indexed as

Acute Kidney InjuryDinoprostoneKidneyRegenerationSOX9 Transcription FactorAnimalsCell DifferentiationCell LineageEpithelial CellsMaleMiceMice, Inbred C57BLRNA-SeqSingle-Cell AnalysisSingle-Cell Gene Expression AnalysisStem CellsDinoprostoneSox9 protein, mouseSOX9 Transcription Factor

Identifiers

PMID38801100
PMCPMC11533080

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.