Evidence map›Paper›PMID 38801099›Full record

ArticleEmerging microbes & infections2024

Molecular mechanisms responsible KPC-135-mediated resistance to ceftazidime-avibactam in ST11-K47 hypervirulent

Qingyu Shi, Siquan Shen, Chengkang Tang, Li Ding, Yan Guo, Yang Yang, Shi Wu, Renru Han, Dandan Yin, Fupin Hu

Abstract read
In one paragraph

Article in Emerging microbes & infections, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Resistance development in KPC-producingMicrobiology spectrum · 2026
    Article
  4. Transcriptomic correlates of ceftazidime-avibactam collateral sensitivity in tigecycline-resistant NDM-producing enterobacter cloacae complex.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Carbapenem-resistant hypervirulentFrontiers in microbiology · 2026
    Review
  10. Emergence of ST11Microbiology spectrum · 2025
    Article
  11. Article
  12. Review
  13. Emergence and evolution of rare ST592Frontiers in cellular and infection microbiology · 2025
    Article
  14. Evolution of ceftazidime-avibactam resistance driven by variation inFrontiers in cellular and infection microbiology · 2025
    Article
  15. Molecular epidemiology of carbapenem-resistant hypervirulentFrontiers in cellular and infection microbiology · 2025
    Article
  16. HypervirulentPathogens & immunity · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Qingyu ShiInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Siquan ShenInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Chengkang TangInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Li DingInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Yan GuoInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Yang YangInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Shi WuInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Renru HanInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Dandan YinInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Fupin HuInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.ORCID 0000-0002-4493-0619

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ceftazidime-avibactam resistance attributable to the

Indexed as

Anti-Bacterial AgentsAzabicyclo CompoundsBacterial Proteinsbeta-LactamasesCeftazidimeDrug CombinationsKlebsiella InfectionsKlebsiella pneumoniaeMicrobial Sensitivity TestsAnimalsBiofilmsDrug Resistance, Multiple, BacterialHumansPlasmidsVirulenceAnti-Bacterial Agentsavibactam, ceftazidime drug combinationAzabicyclo CompoundsBacterial Proteinsbeta-LactamasesCeftazidimeDrug CombinationsblaKPC-135blaKPC-2Carbapenem-resistant Klebsiella pneumoniaceftazidime-avibactamhypervirulentST11-K47Tn6296

Identifiers

PMID38801099
PMCPMC11172257

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.