Evidence map›Paper›PMID 38800708›Full record

ArticleJournal of physics D: Applied physics2024

Capillary-based, multifunctional manipulation of particles and fluids

Zhichao Pei, Zhenhua Tian, Shujie Yang, Liang Shen, Nanjing Hao, Ty D Naquin, Teng Li, Lining Sun, Weibin Rong, Tony Jun Huang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of physics D: Applied physics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhichao PeiDepartment of Mechanical and Electrical Engineering, Harbin Institute of Technology, Harbin, 150080, China.
Zhenhua TianDepartment of Mechanical Engineering, Virginia Polytechnic Institute and State University, VA, 24060, USA.
Shujie YangDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC, 27708, USA.
Liang ShenDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC, 27708, USA.
Nanjing HaoDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC, 27708, USA.
Ty D NaquinDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC, 27708, USA.
Teng LiDepartment of Mechanical Engineering, Virginia Polytechnic Institute and State University, VA, 24060, USA.
Lining SunDepartment of Mechanical and Electrical Engineering, Harbin Institute of Technology, Harbin, 150080, China.
Weibin RongDepartment of Mechanical and Electrical Engineering, Harbin Institute of Technology, Harbin, 150080, China.
Tony Jun HuangDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC, 27708, USA.

Funding

Development of a multifunctional, acoustofluidic 3D bioprinter with single-cell resolutionR01GM144417 · NIGMS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI Zhenhua Tian · 2022 to 2026
$1.8M
NIGMS NIH HHS R01 GM144417
6 · The paper itself

Abstract

Surface acoustic wave (SAW)-enabled acoustofluidic technologies have recently atttracted increasing attention for applications in biology, chemistry, biophysics, and medicine. Most SAW acoustofluidic devices generate acoustic energy which is then transmitted into custom microfabricated polymer-based channels. There are limited studies on delivering this acoustic energy into convenient commercially-available glass tubes for manipulating particles and fluids. Herein, we have constructed a capillary-based SAW acoustofluidic device for multifunctional fluidic and particle manipulation. This device integrates a converging interdigitated transducer to generate focused SAWs on a piezoelectric chip, as well as a glass capillary that transports particles and fluids. To understand the actuation mechanisms underlying this device, we performed finite element simulations by considering piezoelectric, solid mechanic, and pressure acoustic physics. This experimental study shows that the capillary-based SAW acoustofluidic device can perform multiple functions including enriching particles, patterning particles, transporting particles and fluids, as well as generating droplets with controlled sizes. Given the usefulness of these functions, we expect that this acoustofluidic device can be useful in applications such as pharmaceutical manufacturing, biofabrication, and bioanalysis.

Indexed as

acoustofluidicsdroplet generationin-capillary particle manipulationparticle manipulationsurface acoustic waves

Identifiers

PMID38800708
PMCPMC11126230

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.