Evidence map›Paper›PMID 38800678›Full record

ArticleFrontiers in psychology2024

Diagnostic accuracy and clinical utility of the PHQ-2 and GAD-2: a comparison with long-format measures for depression and anxiety.

Jón Ingi Hlynsson, Per Carlbring

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in psychology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05016843 (The Study of Internet-delivered, Transdiagnostic Treatments for Anxiety and Depression), which is not on this map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05016843 nacompletednot on this map

The Study of Internet-delivered, Transdiagnostic Treatments for Anxiety and Depression ("TRAnsdiagnostisk BEhandling (Elektronisk)")

TypeinterventionalSponsorStockholm UniversityRan2021 to 2026Enrolled2,477ConditionsAnxiety Disorders, DepressionArmsTreatment condition: Internet-administered Unified protocol, Treatment condition: Internet-administered Affect phobia treatment, Treatment condition: Waitlist control, Treatment length: 8 weeks, Treatment length: 16 weeks
3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

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  11. Association of performance status, depression, and demographics with advance directive documentation in patients with glioblastoma.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  18. Predictors of impaired awareness of hypoglycaemia and severe hypoglycaemia in adults with type 1 diabetes.Diabetic medicine : a journal of the British Diabetic Association · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jón Ingi HlynssonDepartment of Psychology, University of Iceland, Reykjavík, Iceland.
Per CarlbringDepartment of Psychology, Stockholm University, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Anxiety and depression are highly prevalent and often comorbid mental disorders that are encompassed within the broad category of emotional disorders. The frequent comorbidity of anxiety and depression can pose challenges for accurate diagnosis and treatment which, in turn, highlights the need for reliable measurements that are simultaneously responsive to change and prevent non-response bias. Brief measures of anxiety and depression can potentially increase response rates due to their brevity and ease of administration. This study evaluates the psychometric characteristics, discriminative accuracy, and sensitivity to change of the Generalized Anxiety Disorder 2-item scale (GAD-2) and the Patient Health Questionnaire 2-item scale (PHQ-2) within a clinical population. Method: The sample comprised treatment-seeking participants ( Results: Brief measures can effectively detect individuals who may be eligible for a diagnosis of depression and anxiety, not only prior to but also during and following the completion of psychological treatment. The discriminative ability of the GAD-2 was significantly greater during active treatment and at post-assessment compared with pre-treatment screening, although no such differences were found for the PHQ-2. Finally, endorsing the most severe response option on the GAD-2 and PHQ-2 was associated with a high probability of presenting with clinically relevant anxiety and depressive symptoms. Conclusion: Brief measures of anxiety and depression are viable instruments to screen for and monitor anxiety and depressive symptoms. Clinical trial registration: ClinicalTrials.gov, identifier NCT05016843.

Indexed as

generalized anxiety disorder questionnaireinternet-based psychotherapyitem-option characteristic analysispatient health questionnairepsychometric evaluationreceiver operating characteristic analysis

Identifiers

PMID38800678
PMCPMC11123884

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.