Evidence map›Paper›PMID 38800646›Full record

ArticleLancet regional health. Americas2024

Tuberculosis case notifications and outcomes in Peruvian prisons prior to and during the COVID-19 pandemic: a national-level interrupted time series analysis.

Lena Faust, Guillermo Caceres-Cardenas, Leonardo Martinez, Sophie Huddart, Julia Rios Vidal, Ronald Corilloclla-Torres, Mayra Cordova Ayllon, Andrea Benedetti, Madhukar Pai, César Ugarte-Gil

Abstract read
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Article in Lancet regional health. Americas, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Lena FaustDepartment of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, Canada.
Guillermo Caceres-CardenasInstituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Perú.
Leonardo MartinezSchool of Public Health, Boston University, Boston, USA.
Sophie HuddartDivision of Pulmonary and Critical Care Medicine, University of California San Francisco, San Francisco, USA.
Julia Rios VidalDirección De Control y Prevención de la Tuberculosis (DPCT), Ministerio de Salud, Lima, Perú.
Ronald Corilloclla-TorresSubdireción de Salud Penitenciaria, Instituto Nacional Penitenciario, Lima, Perú.
Mayra Cordova AyllonEstrategia de Tuberculosis, Instituto Nacional Penitenciario, Lima, Perú.
Andrea BenedettiDepartment of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, Canada.
Madhukar PaiDepartment of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, Canada.
César Ugarte-GilInstituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Perú.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The COVID-19 pandemic has significantly disrupted tuberculosis (TB) programs, making it urgent to focus TB elimination efforts on key populations. People experiencing incarceration are at high risk for TB, however, how COVID-19-related disruptions have impacted incarcerated populations with TB is unknown. Methods: Using Peruvian National TB Program data from Jan 2018 to Dec 2021, an interrupted time series of drug-susceptible (DS) TB case notifications pre- and during COVID-19 was conducted (cut-off date: COVID-19 emergency declaration in Peru, 16 March 2020). The effect of TB care occurring pre-vs. during COVID-19 on TB treatment success in the incarcerated and non-incarcerated populations was explored using logistic regression. Findings: DS-TB cases notified in prisons from Jan 2018 to Dec 2021 (n = 10,134) represented 10% of all cases notified in the country (n = 101,507). In the first week of COVID-19, DS-TB case notifications dropped by 61.2% (95% CI: 59.9-62.7%) in the non-incarcerated population and 17.7% (95% CI: 17.5-17.9%) among the incarcerated population. TB treatment success was significantly lower in people receiving TB care entirely during the COVID-19 pandemic vs. before COVID-19 in the non-incarcerated population (OR: 0.81, 95% CI: 0.78-0.85), but not statistically significantly lower in the incarcerated population (OR: 0.88, 95% CI: 0.76-1.01). Incarceration status was not found to modify the effect of COVID-19 period on TB treatment outcomes (OR: 1.07, 95% CI: 0.92-1.25), although treatment success was higher in the incarcerated population (OR [incarcerated vs. not incarcerated, pre-COVID]: 1.52, 95% CI: 1.39-1.67). Interpretation: Both incarcerated and non-incarcerated populations experienced a large drop in DS-TB case notifications (although higher in the non-incarcerated population). Lower TB treatment success among those receiving care during COVID-19 indicates significant TB service disruptions in the overall population. The finding that incarceration at time of diagnosis was associated with treatment success is plausible in Peru given increased screening and stricter treatment monitoring in prisons. Funding: Canadian Institutes of Health Research (Funding Reference Number: 179418) .

Indexed as

Covid-19 pandemicEpidemiologyIncarcerated populationsPeruTuberculosis

Identifiers

PMID38800646
PMCPMC11117008

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.