Evidence map›Paper›PMID 38800514›Full record

ArticleRSC applied polymers2024

Triblock copolymer micelles enhance solubility, permeability and activity of a quorum sensing inhibitor against

Karolina Kasza, Fadi Soukarieh, Manuel Romero, Kim R Hardie, Pratik Gurnani, Miguel Cámara, Cameron Alexander

Abstract read
In one paragraph

Article in RSC applied polymers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Karolina KaszaDivision of Molecular Therapeutics and Formulation, School of Pharmacy, University of Nottingham NG7 2RD UK cameron.alexander@nottingham.ac.uk.ORCID https://orcid.org/0000-0001-5881-1744
Fadi SoukariehNational Biofilms Innovation Centre, School of Life Sciences, Biodiscovery Institute, University Park, University of Nottingham Nottingham NG7 2RD UK.ORCID https://orcid.org/0000-0002-6730-2543
Manuel RomeroNational Biofilms Innovation Centre, School of Life Sciences, Biodiscovery Institute, University Park, University of Nottingham Nottingham NG7 2RD UK.ORCID https://orcid.org/0000-0001-6902-6776
Kim R HardieNational Biofilms Innovation Centre, School of Life Sciences, Biodiscovery Institute, University Park, University of Nottingham Nottingham NG7 2RD UK.ORCID https://orcid.org/0000-0002-4892-2739
Pratik GurnaniUCL School of Pharmacy, University College London 29-39 Brunswick Square London WC1N 1AX UK.ORCID https://orcid.org/0000-0002-6559-5514
Miguel CámaraNational Biofilms Innovation Centre, School of Life Sciences, Biodiscovery Institute, University Park, University of Nottingham Nottingham NG7 2RD UK.ORCID https://orcid.org/0000-0003-4585-7385
Cameron AlexanderDivision of Molecular Therapeutics and Formulation, School of Pharmacy, University of Nottingham NG7 2RD UK cameron.alexander@nottingham.ac.uk.ORCID https://orcid.org/0000-0001-8337-1875

Funding

Wellcome Trust
6 · The paper itself

Abstract

Antimicrobial resistance is a threat to public health for which new treatments are urgently required. The capability of bacteria to form biofilms is of particular concern as it enables high bacterial tolerance to conventional therapies by reducing drug diffusion through the dense, exopolymeric biofilm matrix and the upregulation of antimicrobial resistance machinery. Quorum sensing (QS), a process where bacteria use diffusible chemical signals to coordinate group behaviour, has been shown to be closely interconnected with biofilm formation and bacterial virulence in many top priority pathogens including

Identifiers

PMID38800514
PMCPMC11114570

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.