Evidence map›Paper›PMID 38800191›Full record

ArticleCureus2024

Conjunctival Intraepithelial Neoplasia Mimicking a Pigmentary Lesion in an HIV-Seropositive Indian Male.

Jhimli Ta, Varsha Manade, Megha R Kotecha, Surbhi A Chodvadiya, Jessica Sangwan

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jhimli TaDepartment of Ophthalmology, Dr. D. Y. Patil Medical College, Hospital & Research Centre, Pune, IND.
Varsha ManadeDepartment of Ophthalmology, Dr. D. Y. Patil Medical College, Hospital & Research Centre, Pune, IND.
Megha R KotechaDepartment of Ophthalmology, Dr. D. Y. Patil Medical College, Hospital & Research Centre, Pune, IND.
Surbhi A ChodvadiyaDepartment of Ophthalmology, Dr. D. Y. Patil Medical College, Hospital & Research Centre, Pune, IND.
Jessica SangwanDepartment of Ophthalmology, Dr. D. Y. Patil Medical College, Hospital & Research Centre, Pune, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present the case of a 27-year-old male who presented to our ophthalmology outpatient clinic with a pigmented lesion on the conjunctiva of his right eye. There was no history of ocular trauma or familial ocular complaints, and a thorough evaluation revealed the patient's seropositive status for HIV for the past eight years. The presentation resembled a conjunctival pigmentary lesion, with typical features of ocular surface squamous neoplasia (OSSN) being absent and a demographic incongruent with typical OSSN cases as OSSN typically affects the elderly population. Given the patient's HIV status and the lesion's recent increase in size, a more aggressive treatment approach was warranted. Mass excisional biopsy surgery confirmed conjunctival intraepithelial neoplasia with one positive margin. Adjuvant treatment with mitomycin eye drops (0.04%) resulted in no lesion recurrence at the one-month follow-up. Conjunctival intraepithelial neoplasia can mimic pigmentary lesions in young HIV-positive patients with obvious signs of OSSN being absent. In such cases, the history of seropositivity should be sufficient to suspect it as OSSN and aggressive management measures should be adopted to get best possible outcomes.

Indexed as

conjunctival intraepithelial neoplasiaocular diseases of hivocular oncologyocular surface squamous neoplasia (ossn)pigmented conjunctival lesion

Identifiers

PMID38800191
PMCPMC11126542

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