A National Analysis of Alcohol Withdrawal Syndrome in Patients with Operative Trauma.

Jeffrey Balian, Nam Yong Cho, Amulya Vadlakonda, Joanna Curry, Nikhil Chervu, Konmal Ali, Peyman Benharash

Abstract read

In one paragraph

Article in Surgery open science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

Orthopaedic Trauma in Patients with Documented Alcohol Use: Injury Mechanisms, Clinical Characteristics, and Geriatric Vulnerability.Medical sciences (Basel, Switzerland) · 2026
Article
[Analysis of the misdiagnosis causes and treatment strategies for burns combined with alcohol withdrawal syndrome].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2025
Observational

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5 · Who and what money

Authors and funding

7 authors.

Jeffrey BalianDepartment of Surgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.

Nam Yong ChoDepartment of Surgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.

Amulya VadlakondaDepartment of Surgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.

Joanna CurryDepartment of Surgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.

Nikhil ChervuDepartment of Surgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.

Konmal AliDepartment of Surgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.

Peyman BenharashDepartment of Surgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Alcohol withdrawal syndrome (AWS) presents with a complex spectrum of clinical manifestations that complicate postoperative management. In trauma setting, subjective screening for AWS remains challenging due to the criticality of injury in these patients. We thus identified several patient characteristics and perioperative outcomes associated AWS development. Methods: The 2016-2020 National Inpatient Sample was queried to identify all non-elective adult (≥18 years) hospitalizations for blunt or penetrating trauma undergoing operative management with a diagnosis of AWS. Patients with traumatic brain injury or with a hospital duration of stay <2 days were excluded. Outcomes of interest included in-hospital mortality, perioperative complications, hospitalization costs, length of stay (LOS) and non-home discharge. Results: Of an estimated 2,965,079 operative trauma hospitalizations included for analysis, 36,415 (1.23 %) developed AWS following admission. The AWS cohort demonstrated increased odds of mortality (Adjusted Odds Ratio [AOR] 1.46, 95 % Confidence Interval [95 % CI] 1.23-1.73), along with infectious (AOR 1.73, 95 % CI 1.58-1.88), cardiac (AOR 1.24, 95 % CI 1.06-1.46), and respiratory (AOR 1.96, 95 % CI 1.81-2.11) complications. AWS was associated with prolonged LOS, (β: 3.3 days, 95 % CI: 3.0 to 3.5), greater cost (β: +$8900, 95 % CI $7900-9800) and incremental odds of nonhome discharge (AOR 1.43, 95 % CI 1.34-1.53). Furthermore, male sex, Medicaid insurance status, head injury and thoracic operation were linked with greater odds of development of AWS. Conclusion: In the present study, AWS development was associated with increased odds of in-hospital mortality, perioperative complications, and resource burden. The identification of patient and operative characteristics linked with AWS may improve screening protocols in trauma care.

Indexed as

Alcohol withdrawal syndromeTrauma surgery

Identifiers

PMID38800119

DOI10.1016/j.sopen.2024.05.001

PMCPMC11127230

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