Evidence map›Paper›PMID 38800072›Full record

ArticleBiology methods & protocols2024

Macro-based collagen quantification and segmentation in picrosirius red-stained heart sections using light microscopy.

Julian Kammerer, Alexandra Cirnu, Tatjana Williams, Melanie Hasselmeier, Mike Nörpel, Ruping Chen, Brenda Gerull

Abstract read
In one paragraph

Article in Biology methods & protocols, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  3. Article
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  5. Illuminating Cardiac Remodeling: Insights From [Journal of the American Heart Association · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Julian KammererComprehensive Heart Failure Center, Department of Cardiovascular Genetics, University Hospital Würzburg, Würzburg, 97078, Germany.
Alexandra CirnuComprehensive Heart Failure Center, Department of Cardiovascular Genetics, University Hospital Würzburg, Würzburg, 97078, Germany.ORCID https://orcid.org/0000-0001-9248-0408
Tatjana WilliamsComprehensive Heart Failure Center, Department of Cardiovascular Genetics, University Hospital Würzburg, Würzburg, 97078, Germany.
Melanie HasselmeierComprehensive Heart Failure Center, Department of Cardiovascular Genetics, University Hospital Würzburg, Würzburg, 97078, Germany.
Mike NörpelComprehensive Heart Failure Center, Department of Cardiovascular Genetics, University Hospital Würzburg, Würzburg, 97078, Germany.
Ruping ChenComprehensive Heart Failure Center, Department of Cardiovascular Genetics, University Hospital Würzburg, Würzburg, 97078, Germany.ORCID https://orcid.org/0000-0001-9935-4041
Brenda GerullComprehensive Heart Failure Center, Department of Cardiovascular Genetics, University Hospital Würzburg, Würzburg, 97078, Germany.ORCID https://orcid.org/0000-0002-1363-8826

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Picrosirius red staining constitutes an important and broadly used tool to visualize collagen and fibrosis in various tissues. Although multiple qualitative and quantitative analysis methods to evaluate fibrosis are available, many require specialized devices and software or lack objectivity and scalability. Here, we aimed to develop a versatile and powerful "

Indexed as

collagen quantificationheart segmentationmacro-based analysispicro-sirius red

Identifiers

PMID38800072
PMCPMC11116823

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.