Evidence map›Paper›PMID 38799783›Full record

ArticleKidney medicine2024

APOL1 Kidney Risk Variants and Long-Term Kidney Function in Healthy Middle-Aged Black Individuals: The Atherosclerosis Risk in Communities (ARIC) Study.

Mona D Doshi, Lihua Li, Abhijit S Naik, Christie P Thomas

Abstract read
In one paragraph

Article in Kidney medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Evaluation and Counseling of Living Kidney Donor Candidates.Journal of the American Society of Nephrology : JASN · 2026
    Review
  3. Article
  4. Maintaining kidney health in aging societies: a JSN and ERA call to action.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Review
  5. Article
  6. Article
  7. Kidney medicine · 2024
    Article
4 · The record

Corrections and comments

  • Commented on by
    2024
5 · Who and what money

Authors and funding

4 authors.

Mona D DoshiDivision of Nephrology, Department of Medicine, University of Michigan, Ann Arbor, MI.
Lihua LiDepartment of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY.
Abhijit S NaikDivision of Nephrology, Department of Medicine, University of Michigan, Ann Arbor, MI.
Christie P ThomasDepartment of Medicine and the Iowa Institute of Human Genetics, University of Iowa, Iowa City, IA.

Funding

University of Michigan O'Brien Kidney Translational Core CenterP30DK081943 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PENNATHUR, SUBRAMANIAM · 2008 to 2022
$12.9M
Wake Forest APOLLO Scientific and Data Research CenterU01DK116041 · NIDDK · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Nicholette D. Allred, BARRY Ira FREEDMAN · 2017 to 2026
$8.7M
Defining the molecular landscape of hyperfiltration-mediated glomerular injury using kidney allografts as a model systemK23DK125529 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI NAIK, ABHIJIT S · 2021 to 2025
$962k
NIDDK NIH HHS K23 DK125529NIDDK NIH HHS P30 DK081943NIDDK NIH HHS U01 DK116041
6 · The paper itself

Abstract

Rationale & Objective: The effect of apolipoprotein L1( Study Design: Longitudinal cohort study. Setting & Participants: In total, 5,886 healthy individuals (45-64 years old) enrolled in the Atherosclerosis Risk in Communities study with creatinine-based estimated glomerular filtration rate ≥ 80 mL/min who would be suitable kidney donors. Exposures: Race and Outcomes: Creatinine- and cystatin C-based estimated glomerular filtration rate (eGFRcr-cys) using the CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) 2021 equation, urinary albumin-creatinine ratio (UACR), proportion with chronic kidney disease (CKD) 3a or worse, end-stage kidney disease (ESKD), and death. Analytical Approach: Participants grouped based on race and Results: There were 5,075 Whites (86%), 701 Blacks carrying the low-risk Limitations: Low ascertainment because of death and long follow-up. Conclusions: Among middle-aged individuals,

Indexed as

APOL1Blackhealthykidney functionliving donors

Identifiers

PMID38799783
PMCPMC11127222

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.