Evidence map›Paper›PMID 38799466›Full record

ReviewFrontiers in immunology2024

Glycan-based scaffolds and nanoparticles as drug delivery system in cancer therapy.

Henan Qin, Yibin Teng, Rui Dai, Aman Wang, Jiwei Liu

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Henan Qin *Department of Oncology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Yibin Teng *Department of Oncology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Rui DaiDepartment of Pharmacy, Peking Union Medical University Hospital, Beijing, China.
Aman WangDepartment of Oncology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Jiwei LiuDepartment of Oncology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glycan-based scaffolds are unique in their high specificity, versatility, low immunogenicity, and ability to mimic natural carbohydrates, making them attractive candidates for use in cancer treatment. These scaffolds are made up of glycans, which are biopolymers with well biocompatibility in the human body that can be used for drug delivery. The versatility of glycan-based scaffolds allows for the modulation of drug activity and targeted delivery to specific cells or tissues, which increases the potency of drugs and reduces side effects. Despite their promise, there are still technical challenges in the design and production of glycan-based scaffolds, as well as limitations in their therapeutic efficacy and specificity.

Indexed as

Drug Delivery SystemsNanoparticlesNeoplasmsPolysaccharidesAnimalsAntineoplastic AgentsHumansAntineoplastic AgentsPolysaccharidescancerdrugglycanglycosylationscaffolds

Identifiers

PMID38799466
PMCPMC11116596

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.