Evidence map›Paper›PMID 38799368›Full record

ArticleACS omega2024

New Chalcogen-Functionalized Naphthoquinones: Design, Synthesis, and Evaluation,

Luana da Silva Gomes, Érica de Oliveira Costa, Thuany G Duarte, Thiago S Charret, Raquel C Castiglione, Rafael L Simões, Vinicius D B Pascoal, Thiago H Döring, Fernando de C da Silva, Vitor F Ferreira and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Luana da Silva GomesSupraSelen Laboratory, Department of Organic Chemistry, Institute of Chemistry, Federal University Fluminense, Campus of Valonguinho, Niterói-RJ 24020-141, Brazil.
Érica de Oliveira CostaSupraSelen Laboratory, Department of Organic Chemistry, Institute of Chemistry, Federal University Fluminense, Campus of Valonguinho, Niterói-RJ 24020-141, Brazil.
Thuany G DuarteSupraSelen Laboratory, Department of Organic Chemistry, Institute of Chemistry, Federal University Fluminense, Campus of Valonguinho, Niterói-RJ 24020-141, Brazil.
Thiago S CharretResearch Laboratory of Natural Products and Bioactive Molecules, Nova Friburgo Health Institute, Fluminense Federal University (ISNF-UFF), Nova Friburgo-RJ 28625-650, Brazil.
Raquel C CastiglioneLaboratory for Clinical and Experimental Research on Vascular Biology, Biomedical Center, State University of Rio de Janeiro, Rio de Janeiro-RJ 20550-900, Brazil.
Rafael L SimõesLaboratory of Molecular and Cellular Pharmacology, Roberto Alcântara Gomes Biology Institute, State University of Rio de Janeiro, Rio de Janeiro 20551-030, Brazil.
Vinicius D B PascoalResearch Laboratory of Natural Products and Bioactive Molecules, Nova Friburgo Health Institute, Fluminense Federal University (ISNF-UFF), Nova Friburgo-RJ 28625-650, Brazil.
Thiago H DöringDepartment of Exact Sciences and Education, Federal University of Santa Catarina, Campus Blumenau, Blumenau-SC, 89036-256, Brazil.
Fernando de C da SilvaApplied Organic Synthesis Laboratory (LabSOA), Institute of Chemistry, Universidade Federal Fluminense, Niterói-RJ 24020-141, Brazil.ORCID https://orcid.org/0000-0002-2042-3778
Vitor F FerreiraDepartment of Exact Sciences and Education, Federal University of Santa Catarina, Campus Blumenau, Blumenau-SC 89036-256, Brazil.
Aldo S de OliveiraDepartment of Exact Sciences and Education, Federal University of Santa Catarina, Campus Blumenau, Blumenau-SC, 89036-256, Brazil.ORCID https://orcid.org/0000-0001-7760-4484
Aislan C R F PascoalResearch Laboratory of Natural Products and Bioactive Molecules, Nova Friburgo Health Institute, Fluminense Federal University (ISNF-UFF), Nova Friburgo-RJ 28625-650, Brazil.
André L S CruzPhysiopathology Laboratory, Institute of Medical Sciences, Multidisciplinary Center UFRJ, Federal University of Rio De Janeiro (UFRJ), Macaé-RJ 27930-560, Brazil.
Vanessa NascimentoSupraSelen Laboratory, Department of Organic Chemistry, Institute of Chemistry, Federal University Fluminense, Campus of Valonguinho, Niterói-RJ 24020-141, Brazil.ORCID https://orcid.org/0000-0001-9413-7638

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the growth in the number of patients and the complexity involved in anticancer therapies, new therapeutic approaches are urgent and necessary. In this context, compounds containing the selenium atom can be employed in developing new medicines due to their potential therapeutic efficacy and unique modes of action. Furthermore, tellurium, a previously unknown element, has emerged as a promising possibility in chalcogen-containing compounds. In this study, 13 target compounds (

Identifiers

PMID38799368
PMCPMC11112715

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.