Evidence map›Paper›PMID 38799260›Full record

ArticleEnvironmental epidemiology (Philadelphia, Pa.)2024

Increased vascular stiffness in children exposed in utero but not children exposed postnatally to emissions from a coal mine fire.

Emily J Hemstock, Ashley Bigaran, Shantelle Allgood, Amanda J Wheeler, Marita Dalton, Grant J Williamson, Caroline X Gao, Michael J Abramson, Kazuaki Negishi, Fay H Johnston and 1 more

Abstract read
In one paragraph

Article in Environmental epidemiology (Philadelphia, Pa.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Emily J HemstockMenzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.ORCID https://orcid.org/0000-0003-0228-5508
Ashley BigaranDepartment of Surgery, Faculty of Medicine, Science and Dentistry, University of Melbourne, Melbourne, Victoria, Australia.
Shantelle AllgoodSchool of Rural Health, Monash University, Churchill, Victoria, Australia.
Amanda J WheelerMenzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.
Marita DaltonMenzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.
Grant J WilliamsonMenzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.
Caroline X GaoCentre for Youth Mental Health (Orygen), University of Melbourne, Parkville, Victoria, Australia.
Michael J AbramsonCentre for Air Pollution, Energy and Health Research, NHMRC CRE, Glebe, New South Wales, Australia.
Kazuaki NegishiMenzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.
Fay H JohnstonMenzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.
Graeme R ZoskyMenzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Chronic, low-intensity air pollution exposure has been consistently associated with increased atherosclerosis in adults. However, there was limited research regarding the implications of acute, high-intensity air pollution exposure during childhood. We aimed to determine whether there were any associations between early-life exposure to such an episode and early-life vascular function changes. Methods: We conducted a prospective cohort study of children (<9 years old) who lived in the vicinity of the Hazelwood coal mine fire (n = 206). Vascular function was measured using noninvasive diagnostic methods including carotid intima-media thickness and pulse wave velocity (PWV). Exposure estimates were calculated from prognostic models and location diaries during the exposure period completed by each participant's parent. Linear mixed-effects models were used to determine whether there were any associations between exposure and changes in vascular outcomes at the 3- and 7-year follow-ups and over time. Results: At the 7-year follow-up, each 10 μg/m Conclusion: There was a moderate improvement in vascular stiffness of children exposed to PM

Indexed as

Air pollutionAtherosclerosisEarly childhoodIntima-media thicknessPM2.5SmokeVascular stiffness

Identifiers

PMID38799260
PMCPMC11115982

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.