ArticleDigital health
Language adaptations of mental health interventions: User interaction comparisons with an AI-enabled conversational agent (Wysa) in English and Spanish.
Article in Digital health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07167056 (Artificial Intelligence-Powered Support For Quality Of Life Improvement In Patients With Cancer), which is not on this map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Artificial Intelligence-Powered Support For Quality Of Life Improvement In Patients With Cancer
Who cites it
7 citing papers in PubMed.
- Cultural Prompting Improves the Empathy and Cultural Responsiveness of GPT-Generated Therapy Responses.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2024Trial
- Digital Mental Health Through an Intersectional Lens: A Narrative Review.Healthcare (Basel, Switzerland) · 2026Review
- Digital Psychiatry with Chatbot: Recent Advances and Limitations.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2025Review
- Charting the evolution of artificial intelligence mental health chatbots from rule-based systems to large language models: a systematic review.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2025Article
- Transforming healthcare delivery with conversational AI platforms.NPJ digital medicine · 2025Article
- The algorithmic self: how AI is reshaping human identity, introspection, and agency.Frontiers in psychology · 2025Article
- Artificial intelligence in mental healthcare: transformative potential vs. the necessity of human interaction.Frontiers in psychology · 2024Article
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3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Background: In recent times, digital mental health interventions (DMHIs) have been proven to be efficacious; however, most are available only for English speakers, leaving limited options for non-English languages like Spanish. Research shows that mental health services in one's dominant language show better outcomes. Conversational agents (CAs) offer promise in supporting mental health in non-English populations. This study compared a culturally adapted version of an artificial intelligence (AI)-led mental health app, called Wysa, in Spanish and English. Objectives: To compare user engagement patterns on Wysa-Spanish and Wysa-English and to understand expressions of distress and preferred language in both versions of Wysa. Methods: We adopted a cross-sectional retrospective exploratory design with mixed methods, analyzing users from 10 Spanish-speaking countries between 1 February and 1 August 2022. A quantitative sample A (n = 2767) was used for descriptive statistics, including user engagement metrics with a Wilcoxon test. A subset qualitative sample B (n = 338) was examined for word count differences based on valence, and a content analysis was conducted to examine idioms of distress. Results: Compared to Wysa-English, Wysa-Spanish had more sessions ( Conclusion: Given the high engagement within the Spanish version of Wysa, the findings demonstrate the need for culturally adapted DMHIs among non-English populations, emphasizing the importance of considering linguistic and cultural differences in the development of DMHIs to improve accessibility for diverse populations.
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