Evidence map›Paper›PMID 38798577›Full record

ArticlebioRxiv : the preprint server for biology2024

Spectinamide MBX-4888A exhibits favorable lesion and tissue distribution and promotes treatment shortening in advanced murine models of tuberculosis.

Allison A Bauman, Jansy P Sarathy, Firat Kaya, Lisa M Massoudi, Michael S Scherman, Courtney Hastings, Jiuyu Liu, Min Xie, Elizabeth J Brooks, Michelle E Ramey and 15 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

25 authors.

Allison A Bauman
Jansy P Sarathy
Firat Kaya
Lisa M Massoudi
Michael S Scherman
Courtney Hastings
Jiuyu Liu
Min Xie
Elizabeth J Brooks
Michelle E Ramey
Isabelle L Jones
Noalani D Benedict
Madelyn R Maclaughlin
Jake A Miller-Dawson
Samanthi L Waidyarachchi
Michelle M Butler
Terry L Bowlin
Matthew D Zimmerman
Anne J Lenaerts
Mercedes Gonzalez-JuarreroORCID 0000-0002-4045-2365
Michael A Lyons
Véronique Dartois
Richard E Lee
Gregory T RobertsonORCID 0000-0001-7157-4034

Funding

Development of Novel Proteins Synthesis Inhibitors for MDR TuberculosisR01AI090810 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI LEE, RICHARD E. · 2010 to 2022
$8.9M
NIAID NIH HHS R01 AI090810
6 · The paper itself

Abstract

The spectinamides are novel, narrow-spectrum semisynthetic analogs of spectinomycin, modified to avoid intrinsic efflux by

Identifiers

PMID38798577
PMCPMC11118289

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.