Evidence map›Paper›PMID 38798575›Full record

ArticlebioRxiv : the preprint server for biology2024

Sex-specific single cell-level transcriptomic signatures of Rett syndrome disease progression.

Osman Sharifi, Viktoria Haghani, Kari E Neier, Keith J Fraga, Ian Korf, Sophia M Hakam, Gerald Quon, Nelson Johansen, Dag H Yasui, Janine M LaSalle

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Osman SharifiMedical Microbiology and Immunology, School of Medicine, University of California, Davis, CA 95616.ORCID 0000-0002-4630-2587
Viktoria HaghaniMedical Microbiology and Immunology, School of Medicine, University of California, Davis, CA 95616.ORCID 0000-0002-3700-4027
Kari E NeierMedical Microbiology and Immunology, School of Medicine, University of California, Davis, CA 95616.ORCID 0000-0002-9700-4045
Keith J FragaCellular and Molecular Biology, College of Biological Sciences, University of California, Davis, CA 95616.ORCID 0000-0002-8930-6510
Ian KorfCellular and Molecular Biology, College of Biological Sciences, University of California, Davis, CA 95616.ORCID 0000-0001-5259-6182
Sophia M HakamMedical Microbiology and Immunology, School of Medicine, University of California, Davis, CA 95616.ORCID 0009-0006-1465-6571
Gerald QuonCellular and Molecular Biology, College of Biological Sciences, University of California, Davis, CA 95616.ORCID 0000-0002-1716-0153
Nelson JohansenCellular and Molecular Biology, College of Biological Sciences, University of California, Davis, CA 95616.ORCID 0000-0002-4436-969X
Dag H YasuiMedical Microbiology and Immunology, School of Medicine, University of California, Davis, CA 95616.ORCID 0000-0003-1178-988X
Janine M LaSalleMedical Microbiology and Immunology, School of Medicine, University of California, Davis, CA 95616.ORCID 0000-0002-3480-2031

Funding

Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI KC KENT LLOYD · 2002 to 2026
$84.9M
Research Project: Pathologic Significance of Maternal AutoantibodiesP50HD103526 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEONARD J. ABBEDUTO, Melissa Dawn Bauman · 2020 to 2026
$9.7M
Neuroimmune interactions in Rett syndromeR01AA027075 · NIAAA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LASALLE, JANINE M · 2018 to 2022
$2.9M
UC Davis Shared Astrios Cell SorterS10OD018223 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SHACKLETT, BARBARA L. · 2015 to 2015
$555k
Acquisition of Covaris E220 and Sciclone G3 systems for high throughput sequencinS10OD010786 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI COMAI, LUCA · 2012 to 2012
$311k
NCI NIH HHS P30 CA093373NIAAA NIH HHS R01 AA027075NICHD NIH HHS P50 HD103526NIH HHS S10 OD010786NIH HHS S10 OD018223
6 · The paper itself

Abstract

Dominant X-linked diseases are uncommon due to female X chromosome inactivation (XCI). While random XCI usually protects females against X-linked mutations, Rett syndrome (RTT) is a female neurodevelopmental disorder caused by heterozygous

Identifiers

PMID38798575
PMCPMC11118571

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.