Evidence map›Paper›PMID 38798477›Full record

ArticleResearch square2024

Early physical rehabilitation dosage in the IntensiveCare Unit predicts hospital outcomes after criticalCOVID-19.

Kirby P Mayer, Evan Haezebrouck, Lori M Ginoza, Clarisa Martinez, Minnie Jan, Lori A Michener, Lindsey Fresenko, Ashley A Montgomery-Yates, Anna G Kalema, Amy M Pastva and 3 more

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In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Kirby P MayerUniversity of Kentucky.
Evan HaezebrouckUniversity of Michigan-Ann Arbor.
Lori M GinozaUniversity of Southern California.
Clarisa MartinezUniversity of Southern California.
Minnie JanUniversity of Southern California.
Lori A MichenerUniversity of Southern California.
Lindsey FresenkoUniversity of Kentucky.
Ashley A Montgomery-YatesUniversity of Kentucky.
Anna G KalemaUniversity of Kentucky.
Amy M PastvaDuke University.
Michelle BiehlCleveland Clinic.
Matthew F MartVanderbilt University.
Joshua K JohnsonDuke University.

Funding

Institutional Career Development CoreKL2TR002245 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Julie A. Bastarache · 2017 to 2026
$9.3M
Cellular and Physical Function Outcomes Leading to Failed Muscle Recovery After Critical IllnessK23AR079583 · NIAMS · UNIVERSITY OF KENTUCKY · PI Kirby P Mayer · 2022 to 2026
$744k
NCATS NIH HHS KL2 TR002245NIAMS NIH HHS K23 AR079583NIMHD NIH HHS L32 MD017732
6 · The paper itself

Abstract

Objective: to examine the relationship between physical rehabilitation parameters including a novel approach to quantifying dosage with hospital outcomes for patients with critical COVID-19. Design: Retrospective practice analysis from March 5, 2020, to April 15, 2021. Setting: Intensive care units (ICU) at four medical institutions. Patients: n = 3,780 adults with ICU admission and diagnosis of COVID-19. Interventions: We measured the physical rehabilitation treatment delivered in ICU and patient outcomes: 1) mortality; 2) discharge disposition; and 3) physical function at hospital discharge measured by the Activity Measure-Post Acute Care (AM-PAC) "6-Clicks" (6-24, 24=greater functional independence). Physical rehabilitation dosage was defined as the average mobility level scores in the first three sessions (a surrogate measure of intensity) multiplied by the rehabilitation frequency (PT + OT frequency in hospital). Measurements and Main Results: The cohort was a mean 64 ± 16 years old, 41% female, mean BMI of 32 ± 9 kg/m Conclusions: Greater physical rehabilitation exposure early in the ICU is associated with physical function at hospital discharge.

Indexed as

COVIDcritical illnessearly mobilizationoccupational therapyPhsyical rehabilitationphysical therapy

Identifiers

PMID38798477
PMCPMC11118711

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.