Evidence map›Paper›PMID 38798296›Full record

ArticleVeterinary world2024

Production and characterization of immunoglobulin G anti-rLipL32 antibody as a biomarker for the diagnosis of leptospirosis.

Susanti Susanti, Pratiwi Pudjilestari Sudarmono, N L P Indi Dharmayanti, Prasandhya Astagiri Yusuf

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary world, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Susanti SusantiDoctoral Program in Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia.
Pratiwi Pudjilestari SudarmonoDepartment of Microbiology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia.
N L P Indi DharmayantiResearch Center for Veterinary Science, Research Organization for Health, National Research and Innovation Agency, Bogor, 16911, Indonesia.
Prasandhya Astagiri YusufMedical Physiology Biophysics Department and Medical Technology IMERI, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: Microscopic agglutination test (MAT) for the diagnosis of leptospirosis requires live cultures and is serovar-specific, while polymerase chain reaction (PCR) requires expensive equipment and sample preparation. The rLipL32 protein is conserved and can be used for the production of immunoglobulin G (IgG) anti-rLipL32 antibody, which can be used as a biomarker for leptospirosis diagnosis. This study aimed to produce and characterize an IgG anti-rLipL32 antibody as a biomarker for leptospirosis diagnosis. Materials and Methods: Results: PCR was able to amplify the LipL32 gene from Conclusion: IgG anti-rLipL32 antibody has high specificity and sensitivity against

Indexed as

anti-rLipL32 serumimmunoglobulin G anti-rLipL32 antibodyLeptospirarLipL32 protein

Identifiers

PMID38798296
PMCPMC11111714

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.