Evidence map›Paper›PMID 38798209›Full record

ReviewEndocrine, metabolic & immune disorders drug targets2025

The "Magnificent Seven" in Oral and Systemic Health against COVID-19.

Marina Di Domenico, Alessandro Motta, Tommaso Dai Pra, Stefania Cantore, Mario Dioguardi, Eugenia Rosalinda Zanella, Roberto Arrigoni, Danila De Vito, Filiberto Mastrangelo

Abstract readReview
PubMed Publisher
In one paragraph

Review in Endocrine, metabolic & immune disorders drug targets, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marina Di DomenicoDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.
Alessandro MottaOperative Unit of Oral Surgery for Special Needs and Dentistry, Trento Hospital, Borgo Valsugana, Trento, Italy.
Tommaso Dai PraOperative Unit of Oral Surgery for Special Needs and Dentistry, Trento Hospital, Borgo Valsugana, Trento, Italy.
Stefania CantoreDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.
Mario DioguardiDepartment of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
Eugenia Rosalinda ZanellaCandiolo Cancer Institute, IRCCS-FPO, Laboratory of Translational Cancer Medicine, Turin, Italy.
Roberto ArrigoniCNR Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies (IBIOM), Bari, Italy.
Danila De VitoSchool of Medicine, University of Bari, Aldo Moro, Bari, Italy.
Filiberto MastrangeloDepartment of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.

Funding

Campania Region-PORFESR CAMPANIA 2014-2020-OS 1.3-ACTION 1.3.1UNICAMPANIA CUP B63C22001210007, SURF 21058BP000000020
6 · The paper itself

Abstract

The COVID-19 pandemic impacted all areas of daily life, including medical care. Unfortunately, to date, no specific treatments have been found for the cure of this disease, and therefore, it is advisable to implement all possible strategies to prevent infection. In this context, it is important to better define the role of all behaviors, in particular nutrition, in order to establish whether these can both prevent infection and improve the outcome of the disease in patients with COVID-19. There is sufficient evidence to demonstrate that immune response can be weakened by inadequate nutrition. Nutrition management and treatment are very important to enhance the immune response of an infected person against RNA viral infection. A complete nutritional assessment should include anthropometric, dietary, and laboratorial assessment, as well as a multidisciplinary discussion about the patient's clinical condition. In this way, it is possible to establish an individualized nutritional approach to contribute to improving clinical and nutritional prognoses. From this point of view, diet, through intake of vitamins and trace elements and maintaining adequate functioning of the intestinal barrier, can reduce the severity of the COVID-19 infection. In this study, we provide an overview of the effects of diet on COVID-19 infection in non-cancer patients. This notion needs to be further evaluated, and thus, identification, characterization, and targeting of the right nutrition principles related to the management of patients with COVID-19 are likely to improve outcomes and may prevent the infection or lead to a cure.

Indexed as

COVID-19Nutritional StatusOral HealthHumansNutrition AssessmentSARS-CoV-2COVID-19metabolismmicrobiotanutritiontranslational medicine.vitamins

Identifiers

PMID38798209

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.