Evidence map›Paper›PMID 38798116›Full record

ArticleHuman brain mapping2024

Heritability of cerebellar subregion volumes in adolescent and young adult twins.

Lachlan T Strike, Rebecca Kerestes, Katie L McMahon, Greig I de Zubicaray, Ian H Harding, Sarah E Medland

Abstract readTwin Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Human brain mapping, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lachlan T StrikePsychiatric Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Australia.ORCID 0000-0003-2885-5898
Rebecca KerestesDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, Australia.ORCID 0000-0003-1298-9904
Katie L McMahonSchool of Clinical Sciences, Centre for Biomedical Technologies, Queensland University of Technology, Brisbane, Queensland, Australia.ORCID 0000-0002-6357-615X
Greig I de ZubicaraySchool of Psychology and Counselling, Faculty of Health, Queensland University of Technology, Kelvin Grove, Queensland, Australia.ORCID 0000-0003-4506-0579
Ian H HardingDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, Australia.ORCID 0000-0002-6843-9592
Sarah E MedlandPsychiatric Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Australia.ORCID 0000-0003-1382-380X

Funding

Genetic influences on the brain: A twin imaging studyR01HD050735 · NICHD · QUEENSLAND INSTITUTE OF MEDICAL RESEARCH · PI WRIGHT, MARGARET JANE · 2007 to 2011
$2.6M
National Health and Medical Research Council 1009064National Health and Medical Research Council 1078756National Health and Medical Research Council 496682National Health and Medical Research Council APP1158127National Health and Medical Research Council APP1172917NICHD NIH HHS R01 HD050735
6 · The paper itself

Abstract

Twin studies have found gross cerebellar volume to be highly heritable. However, whether fine-grained regional volumes within the cerebellum are similarly heritable is still being determined. Anatomical MRI scans from two independent datasets (QTIM: Queensland Twin IMaging, N = 798, mean age 22.1 years; QTAB: Queensland Twin Adolescent Brain, N = 396, mean age 11.3 years) were combined with an optimised and automated cerebellum parcellation algorithm to segment and measure 28 cerebellar regions. We show that the heritability of regional volumetric measures varies widely across the cerebellum (

Indexed as

CerebellumMagnetic Resonance ImagingAdolescentChildHumansOrgan SizeTwins, MonozygoticYoung Adultcerebellumgeneticsheritabilitymagnetic resonance imagingtwin study

Identifiers

PMID38798116
PMCPMC11128777

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.