Evidence map›Paper›PMID 38796856›Full record

ArticleThe Journal of international medical research2024

Serum C-reactive protein value on day 14 as a possible prognostic factor of aneurysmal subarachnoid hemorrhage.

Fukutaro Ohgaki, Junya Tatezuki, Yasunori Takemoto, Kazuki Miyazaki, Yasuhiko Mochimatsu

Abstract read
In one paragraph

Article in The Journal of international medical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Fukutaro OhgakiDepartment of Neurosurgery, Yokohama City Minato Red Cross Hospital, Yokohama, Kanagawa, Japan.ORCID 0000-0001-7986-8811
Junya TatezukiDepartment of Neurosurgery, Yokohama City Minato Red Cross Hospital, Yokohama, Kanagawa, Japan.
Yasunori TakemotoDepartment of Neurosurgery, Yokohama City Minato Red Cross Hospital, Yokohama, Kanagawa, Japan.
Kazuki MiyazakiDepartment of Neurosurgery, Yokohama City Minato Red Cross Hospital, Yokohama, Kanagawa, Japan.
Yasuhiko MochimatsuDepartment of Neurosurgery, Yokohama City Minato Red Cross Hospital, Yokohama, Kanagawa, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveSerum C-reactive protein (CRP), as a reflection of early brain injury at onset, is a prognostic factor in aneurysmal subarachnoid hemorrhage (aSAH). However, in some severe cases, patients exhibit a good prognosis despite their elevated serum CRP level. Therefore, we examined the relationship between serum CRP transitions in the acute phase of aSAH and the prognosis.

methodsWe recruited 63 patients with aSAH and retrospectively analyzed the relationships between the serum CRP transitions during the acute phase and the prognosis, patient background, and clinical course.

resultsSerum CRP values on days 1, 3, and 14 were significantly lower in the good prognosis group than those in the poor prognosis group. Moreover, serum CRP values on days 1 and 14 significantly affected the prognosis in the multiple regression analysis.

conclusionsA low serum CRP value on day 14, in addition to that on day 1 as reported previously, is associated with a good prognosis of aSAH. Furthermore, a good prognosis of aSAH is determined not only by absence of early brain injury at onset but also by appropriate management to obtain a low serum CRP value on day 14.

Indexed as

C-Reactive ProteinSubarachnoid HemorrhageAdultAgedBiomarkersFemaleHumansMaleMiddle AgedPrognosisRetrospective StudiesTime FactorsBiomarkersC-Reactive ProteinAneurysmal subarachnoid hemorrhageC-reactive proteindelayed cerebral ischemiaearly mobilizationprognostic factorrehabilitation

Identifiers

PMID38796856
PMCPMC11129573

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.