Evidence map›Paper›PMID 38796687›Full record

ArticleJNCI cancer spectrum2024

Emergency department involvement in the diagnosis of cancer among older adults: a SEER-Medicare study.

Caroline A Thompson, Paige Sheridan, Eman Metwally, Sharon Peacock Hinton, Megan A Mullins, Ellis C Dillon, Matthew Thompson, Nicholas Pettit, Allison W Kurian, Sandi L Pruitt and 1 more

Abstract read
In one paragraph

Article in JNCI cancer spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
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  5. Exploring Clinical Pathways to a Metastatic Lung Cancer Diagnosis: A Latent Class Analysis Using North Carolina Multipayer Claims Data.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Article
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  14. Observational
  15. Article
  16. Emergency department use before cancer diagnosis in Ontario, Canada: a population-based study.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2024
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Caroline A ThompsonDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.ORCID 0000-0001-9990-9756
Paige SheridanAetion, Inc, New York, NY, USA.
Eman MetwallyDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.
Sharon Peacock HintonDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.
Megan A MullinsPeter O'Donnell Jr School of Public Health, UT Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0003-2753-9068
Ellis C DillonCenter on Aging, UConn Health, Farmington, CT, USA.
Matthew ThompsonDepartment of Family Medicine, University of Washington, Seattle, WA, USA.
Nicholas PettitDepartment of Emergency Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Allison W KurianStanford University School of Medicine, Stanford, CA, USA.
Sandi L PruittPeter O'Donnell Jr School of Public Health, UT Southwestern Medical Center, Dallas, TX, USA.
Georgios LyratzopoulosEpidemiology of Cancer Healthcare & Outcomes, Institute of Epidemiology & Health Care, University College London, London, UK.

Funding

Diagnosis of Cancer in the Emergency Room - Explaining Persistent Disparities - Diversity SupplementR01CA264176 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI THOMPSON, CAROLINE AVERY · 2021 to 2025
$2.0M
American Cancer SocietyCancer Research UKNCI NIH HHS HHSN261201800009CNCI NIH HHS HHSN261201800009INCI NIH HHS HHSN261201800015CNCI NIH HHS HHSN261201800015INCI NIH HHS HHSN261201800032CNCI NIH HHS HHSN261201800032INCI NIH HHS R01 CA264176NCI NIH HHS R01-CA-264176NIH HHS
6 · The paper itself

Abstract

backgroundInternationally, 20% to 50% of cancer is diagnosed through emergency presentation, which is associated with lower survival, poor patient experience, and socioeconomic disparities, but population-based evidence about emergency diagnosis in the United States is limited. We estimated emergency department (ED) involvement in the diagnosis of cancer in a nationally representative population of older US adults, and its association with sociodemographic, clinical, and tumor characteristics.

methodsWe analyzed Surveillance, Epidemiology, and End Results Program-Medicare data for Medicare beneficiaries (≥66 years old) with a diagnosis of female breast, colorectal, lung, and prostate cancers (2008-2017), defining their earliest cancer-related claim as their index date, and patients who visited the ED 0 to 30 days before their index date to have "ED involvement" in their diagnosis, with stratification as 0 to 7 or 8 to 30 days. We estimated covariate-adjusted associations of patient age, sex, race and ethnicity, marital status, comorbidity score, tumor stage, year of diagnosis, rurality, and census-tract poverty with ED involvement using modified Poisson regression.

resultsAmong 614 748 patients, 23% had ED involvement, with 18% visiting the ED in the 0 to 7 days before their index date. This rate varied greatly by tumor site, with breast cancer at 8%, colorectal cancer at 39%, lung cancer at 40%, and prostate cancer at 7%. In adjusted models, older age, female sex, non-Hispanic Black and Native Hawaiian or Other Pacific Islander race, being unmarried, recent year of diagnosis, later-stage disease, comorbidities, and poverty were associated with ED involvement.

conclusionsThe ED may be involved in the initial identification of cancer for 1 in 5 patients. Earlier, system-level identification of cancer in non-ED settings should be prioritized, especially among underserved populations.

Indexed as

Breast NeoplasmsColorectal NeoplasmsEmergency Service, HospitalLung NeoplasmsMedicareNeoplasmsProstatic NeoplasmsSEER ProgramAgedAged, 80 and overAge FactorsBlack or African AmericanComorbidityFemaleHumansMale

Identifiers

PMID38796687
PMCPMC11193434

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.