Evidence map›Paper›PMID 38796680›Full record

ArticleThe British journal of radiology2024

Verification of a simplified aneurysm dimensionless flow parameter to predict intracranial aneurysm rupture status.

Runlin Yang, Yifan Ren, Hong Kuan Kok, Paul D Smith, Parham Mohsenzadeh Kebria, Abbas Khosravi, Julian Maingard, Melissa Yeo, Jonathan Hall, Michelle Foo and 5 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The British journal of radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

15 authors.

Runlin YangDepartment of Radiology, Austin Hospital, Melbourne, 3084, Australia.ORCID 0000-0003-0736-4408
Yifan RenInterventional Radiology Service-Department of Radiology, Austin Hospital, Melbourne, 3084, Australia.
Hong Kuan KokInterventional Radiology Service, Northern Health Radiology, Melbourne, 3076, Australia.
Paul D SmithMelbourne Medical School, The University of Melbourne, Parkville, 3052, Australia.
Parham Mohsenzadeh KebriaInstitute for Intelligent Systems Research and Innovation, Deakin University, Waurn Ponds, 3216, Australia.
Abbas KhosraviInstitute for Intelligent Systems Research and Innovation, Deakin University, Waurn Ponds, 3216, Australia.
Julian MaingardInterventional Radiology Service-Department of Radiology, Austin Hospital, Melbourne, 3084, Australia.
Melissa YeoDepartment of Radiology, Western Health, Melbourne, 3011, Australia.
Jonathan HallDepartment of Radiology, St Vincent's Hospital Melbourne, Melbourne, 3065, Australia.
Michelle FooInterventional Radiology Service-Department of Radiology, Austin Hospital, Melbourne, 3084, Australia.
Kevin ZhouDepartment of Radiology, Monash Health, Monash University, Melbourne, 3168, Australia.
Ashu JhambInterventional Radiology Service-Department of Radiology, St Vincent's Hospital Melbourne, Melbourne, 3065, Australia.
Jeremy RussellDepartment of Neurosurgery, Austin Hospital, Melbourne, 3084, Australia.
Mark BrooksInterventional Radiology Service-Department of Radiology, Austin Hospital, Melbourne, 3084, Australia.
Hamed AsadiInterventional Neuroradiology Service-Department of Radiology, Austin Hospital, Melbourne, 3084, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAneurysm number (An) is a novel prediction tool utilizing parameters of pulsatility index (PI) and aneurysm geometry. An has been shown to have the potential to differentiate intracranial aneurysm (IA) rupture status. The objective of this study is to investigate the feasibility and accuracy of An for IA rupture status prediction using Australian based clinical data.

methodsA retrospective study was conducted across three tertiary referral hospitals between November 2017 and November 2020 and all saccular IAs with known rupture status were included. Two sets of An values were calculated based on two sets of PI values previously reported in the literature.

resultsFive hundred and four IA cases were included in this study. The results demonstrated no significant difference between ruptured and unruptured status when using An ≥1 as the discriminator. Further analysis showed no strong correlation between An and IA subtypes. The area under the curve (AUC) indicated poor performance in predicting rupture status (AUC1 = 0.55 and AUC2 = 0.56).

conclusionsThis study does not support An ≥1 as a reliable parameter to predict the rupture status of IAs based on a retrospective cohort. Although the concept of An is supported by hemodynamic aneurysm theory, further research is needed before it can be applied in the clinical setting. ADVANCES IN KNOWLEDGE: This study demonstrates that the novel prediction tool, An, proposed in 2020 is not reliable and that further research of this hemodynamic model is needed before it can be incorporated into the prediction of IA rupture status.

Indexed as

Aneurysm, RupturedIntracranial AneurysmAdultAgedAustraliaCerebral AngiographyFeasibility StudiesFemaleHumansMaleMiddle AgedPredictive Value of TestsPulsatile FlowRetrospective Studieshaemodynamicintracranial aneurysmmorphologypulsatility indexrupture

Identifiers

PMID38796680
PMCPMC11186560

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.