Evidence map›Paper›PMID 38796472›Full record

ArticleNature communications2024

Rab30 facilitates lipid homeostasis during fasting.

Danielle M Smith, Brian Y Liu, Michael J Wolfgang

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Danielle M SmithDepartment of Physiology, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Brian Y LiuDepartment of Physiology, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.ORCID http://orcid.org/0009-0005-6856-5491
Michael J WolfgangDepartment of Physiology, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA. mwolfga1@jhmi.edu.ORCID http://orcid.org/0000-0003-2349-8414

Funding

Coordination of hepatic fatty acid metabolismR01DK120530 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI WOLFGANG, MICHAEL J. · 2020 to 2024
$2.0M
LSM880 Laser-scanning Microscope with Airyscan ModuleS10OD023548 · OD · JOHNS HOPKINS UNIVERSITY · PI KUO, SCOT CHARLES · 2018 to 2018
$439k
NIDDK NIH HHS R01 DK120530NIH HHS S10 OD023548U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (National Institute of Diabetes & Digestive & Kidney Diseases) R01DK120530
6 · The paper itself

Abstract

To facilitate inter-tissue communication and the exchange of proteins, lipoproteins, and metabolites with the circulation, hepatocytes have an intricate and efficient intracellular trafficking system regulated by small Rab GTPases. Here, we show that Rab30 is induced in the mouse liver by fasting, which is amplified in liver-specific carnitine palmitoyltransferase 2 knockout mice (Cpt2

Indexed as

Carnitine O-PalmitoyltransferaseFastingHepatocytesHomeostasisLipid MetabolismLiverMice, Knockoutrab GTP-Binding ProteinsAnimalsCholesterolGolgi ApparatusMaleMiceMice, Inbred C57BLTriglyceridesCarnitine O-PalmitoyltransferaseCholesterolRab30 protein, mouserab GTP-Binding ProteinsTriglycerides

Identifiers

PMID38796472
PMCPMC11127972

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.