Evidence map›Paper›PMID 38795747›Full record

ArticleThe Journal of nutrition2024

PACE: a Novel Eating Behavior Phenotype to Assess Risk for Obesity in Middle Childhood.

Kathleen L Keller, Alaina L Pearce, Bari Fuchs, Barbara J Rolls, Stephen J Wilson, Charles F Geier, Emma Rose, Hugh Garavan

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03341247 (Brain Mechanisms of Overeating in Children), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03341247 completednot on this map

Brain Mechanisms of Overeating in Children

TypeobservationalSponsorPenn State UniversityRan2018 to 2023Enrolled254ConditionsPediatric Obesity, Inhibition, Decision Making, fMRI
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kathleen L KellerDepartment of Nutritional Sciences, The Pennsylvania State University, PA, United States; Department of Food Science, The Pennsylvania State University, PA, United States. Electronic address: klk37@psu.edu.
Alaina L PearceDepartment of Nutritional Sciences, The Pennsylvania State University, PA, United States.
Bari FuchsDepartment of Nutritional Sciences, The Pennsylvania State University, PA, United States.
Barbara J RollsDepartment of Nutritional Sciences, The Pennsylvania State University, PA, United States.
Stephen J WilsonDepartment of Psychology, The Pennsylvania State University, PA, United States.
Charles F GeierDepartment of Human Development and Family Studies, The Pennsylvania State University, State College, PA, United States.
Emma RoseDepartment of Psychology, The Pennsylvania State University, PA, United States.
Hugh GaravanDepartment of Psychological Sciences, University of Vermont, VT, United States.

Funding

Penn State Institutional Career Development CoreKL2TR002015 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI VAN SCOY, LAUREN JODI · 2016 to 2025
$7.8M
Brain Mechanisms of Overeating in ChildrenR01DK110060 · NIDDK · PENNSYLVANIA STATE UNIVERSITY, THE · PI KELLER, KATHLEEN L · 2017 to 2021
$2.4M
Characterizing resilience to food-cue induced overeating in childrenR01DK126050 · NIDDK · PENNSYLVANIA STATE UNIVERSITY, THE · PI KELLER, KATHLEEN L · 2021 to 2024
$2.3M
NCATS NIH HHS KL2 TR002015NIDDK NIH HHS R01 DK110060NIDDK NIH HHS R01 DK126050
6 · The paper itself

Abstract

backgroundBehavioral phenotypes that predict future weight gain are needed to identify children susceptible to obesity.

objectivesThis prospective study developed an eating behavior risk score to predict change in adiposity over 1 y in children.

methodsData from 6 baseline visits (Time 1, T1) and a 1-y follow-up visit (Time 2, T2) were collected from 76, 7- to 8-y-old healthy children recruited from Central Pennsylvania. At T1, children had body mass index (BMI) percentiles <90 and were classified with either high (n = 33; maternal BMI ≥30 kg/m

resultsFour eating measures-Portion susceptibility, Appetitive traits, loss of control eating, and eating rate-were combined into a standardized summary score called PACE. PACE improved the baseline model to predict 80% variance in T2 FMI. PACE was positively associated with the increase in FMI in children from T1 to T2, independent of familial risk (r = 0.58, P < 0.001). Although PACE was higher in girls than boys (P < 0.05), it did not differ by familial risk, income, or education.

conclusionsPACE represents a cumulative eating behavior risk score that predicts adiposity gain over 1 y in middle childhood. If PACE similarly predicts adiposity gain in a cohort with greater racial and socioeconomic diversity, it will inform the development of interventions to prevent obesity. This trial was registered at clinicaltrials.gov as NCT03341247.

Indexed as

Body Mass IndexFeeding BehaviorPediatric ObesityAdiposityChildFemaleHumansMalePennsylvaniaPhenotypeProspective StudiesRisk Factorsappetitive traitsbehavioral phenotypeschildreneating in the absence of hungereating ratepediatric obesityportion size susceptibility

Identifiers

PMID38795747
PMCPMC11282498

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.