Evidence map›Paper›PMID 38795311›Full record

ArticlePain and therapy2024

Efficacy and Adverse Effects of IV Morphine for Burn Pain Management in the Emergency Department: An Observational Study.

Francesco Coletta, Rossella Pirolli, Raffaele Annunziata, Manuela Nugnes, Antonio Tommasello, Romolo Villani, Luca Gregorio Giaccari, Maria Beatrice Passavanti, Maria Caterina Pace, Pasquale Sansone

Abstract read
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In one paragraph

Article in Pain and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Francesco ColettaEmergency and Acceptance Department, Anesthesia, Emergency and Burn Intensive Care Unit, "A.O.R. N. A. Cardarelli", Naples, Italy.
Rossella PirolliEmergency and Acceptance Department, Anesthesia, Emergency and Burn Intensive Care Unit, "A.O.R. N. A. Cardarelli", Naples, Italy.
Raffaele AnnunziataEmergency and Acceptance Department, Anesthesia, Emergency and Burn Intensive Care Unit, "A.O.R. N. A. Cardarelli", Naples, Italy.
Manuela NugnesEmergency and Acceptance Department, Anesthesia, Emergency and Burn Intensive Care Unit, "A.O.R. N. A. Cardarelli", Naples, Italy.
Antonio TommaselloEmergency and Acceptance Department, Anesthesia, Emergency and Burn Intensive Care Unit, "A.O.R. N. A. Cardarelli", Naples, Italy.
Romolo VillaniEmergency and Acceptance Department, Anesthesia, Emergency and Burn Intensive Care Unit, "A.O.R. N. A. Cardarelli", Naples, Italy.
Luca Gregorio GiaccariDepartment of Woman, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", Piazza Luigi Miraglia, 2, Naples, Italy. lucagregorio.giaccari@gmail.com.
Maria Beatrice PassavantiDepartment of Woman, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", Piazza Luigi Miraglia, 2, Naples, Italy.
Maria Caterina PaceDepartment of Woman, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", Piazza Luigi Miraglia, 2, Naples, Italy.
Pasquale SansoneDepartment of Woman, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", Piazza Luigi Miraglia, 2, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe management of pain following a burn is extremely complex because of the multifactorial nature of burn pain (nociceptive and neuropathic). In the pre-hospital setting and emergency department (ED), the main goal of acute pain management is to reduce the patient's pain, allowing them to maintain function and to prevent the chronification of pain. Opioids are used as first-line treatment in management of burn pain. The aim of our study was to evaluate the efficacy and adverse effects of intravenous (IV) morphine for burn pain management in the ED and to evaluate pain management in the pre-hospital setting.

methodsIn this single-center observational study, patients presenting with second- and third-degree burns were enrolled in our ED. Numerical Rating Scale (NRS) and Burn Specific Pain Anxiety Scale (BSPAS) were performed at ED admission and after 1 h. Pain medications administered before arrival in the ED were reported by the rescue team. All patients received IV acetaminophen every 8 h and IV morphine according NRS.

resultsThirty patients were included in this study. At the time of arrival to the ED, > 90% of the patients reported severe pain; 95.8% of them received IV morphine to achieve pain relief. After 1 h, > 65% of patients had NRS < 3. The total amount of IV morphine was 18.12 ± 4.26 mg in the first hour. No adverse events were recorded. The BSPAS on admission to the ED was 34.8 ± 5.6, indicating severe anxiety. After 1 h, BSPAS was 12.8 ± 4.8, indicating mild anxiety.

conclusionIV morphine used for burn pain management in the emergency setting significantly improves patient outcomes in terms of pain. IV morphine also reduced anxiety scores at 1 h.

Indexed as

AnxietyBurn centerEmergency departmentMorphinePain

Identifiers

PMID38795311
PMCPMC11254875

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.