Evidence map›Paper›PMID 38795279›Full record

ArticleSleep & breathing = Schlaf & Atmung2024

Sleep apnea patients with epiglottic collapse elevate their larynx more with swallowing; videofluoroscopic swallowing study of 80 patients.

Hyung Chae Yang, Alphonse Umugire, Min-Keun Song, Sung Chung Man, Hong Chan Kim, Jisun Kim, Daniel Vena, Phillip Huyett, Insung Choi, Andrew D Wellman

Abstract read
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In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Sleep endoscopy in obstructive sleep apnea: analysis of pharyngeal collapse patterns and correlation with body mass index.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hyung Chae Yang *Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Medical School and Hospital, Gwangju, South Korea.
Alphonse Umugire *Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Medical School and Hospital, Gwangju, South Korea.
Min-Keun SongDepartment of Physical and Rehabilitation Medicine, Chonnam National University Medical School and Hospital, 42 Jebong-ro Dong-gu, Gwangju, 61479, South Korea. drsongmk@jnu.ac.kr.ORCID 0000-0001-8186-5345
Sung Chung ManDepartment of Otolaryngology-Head and Neck Surgery, Chonnam National University Medical School and Hospital, Gwangju, South Korea.
Hong Chan KimDepartment of Otolaryngology-Head and Neck Surgery, Chonnam National University Medical School and Hospital, Gwangju, South Korea.
Jisun KimDepartment of Otolaryngology-Head and Neck Surgery, Chonnam National University Medical School and Hospital, Gwangju, South Korea.
Daniel VenaDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Phillip HuyettDepartment of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear and Harvard Medical School, Boston, MA, USA.
Insung ChoiDepartment of Physical and Rehabilitation Medicine, Chonnam National University Medical School and Hospital, 42 Jebong-ro Dong-gu, Gwangju, 61479, South Korea. drchoiis@daum.net.
Andrew D WellmanDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

Funding

Chonnam National University Hospital BCRI24029Ministry of Science and ICT, South Korea NRF-2022R1C1C1010136
6 · The paper itself

Abstract

objectiveThe epiglottis plays an integral role in the swallowing mechanism and is also implicated as an obstruction site in obstructive sleep apnea (OSA). The underlying causes of epiglottic collapse during sleep remain unclear. This study aimed to investigate the cognitive functions using the Loewenstein Occupational Therapy Cognitive Assessment (LOTCA) and the neurophysiological and anatomical factors using videofluoroscopic swallowing studies (VFSS). We compared patients with OSA exhibiting epiglottic collapse to those without, assessing differences in anatomical or neurophysiological characteristics.

methodsThe study included 12 patients with epiglottic collapse (Epi-group) and 68 without (non-Epi group), all undergoing overnight polysomnography (PSG), drug-induced sleep endoscopy (DISE), LOTCA, and VFSS. Oral transit time (OTT), pharyngeal delay time (PDT), and pharyngeal transit time (PTT) were considered as neurophysiological traits, and laryngeal elevation length (LE) as anatomical trait, and were measured across various test diets (10 ml of liquid, soft, or solid).

resultsThe study comprised 80 individuals, 57 men and 23 women, with no significant age, sex, body mass index or PSG parameters between groups, or DISE findings, with the exception of epiglottic collapse. Swallowing metrics from VFSS were normal, with no differences in OTT, PDT, PTT, or LOTCA scores. Notably, patients with epiglottic collapse showed a greater laryngeal elevation when swallowing soft and solid foods (p = 0.025 and p = 0.048, respectively).

conclusionsPatients with epiglottic collapse do not exhibit neurophysiological or cognitive impairments when compared to non-Epi group. However, the Epi-group displayed a significantly increased laryngeal elevation length. This suggests that anatomical factors may have a more substantial role in the development of epiglottic collapse than neurophysiological factors.

Indexed as

DeglutitionEpiglottisPolysomnographySleep Apnea, ObstructiveAdultAgedDeglutition DisordersFemaleFluoroscopyHumansLarynxMaleMiddle AgedVideo RecordingAnatomical factorsEpiglottis collapseObstructive sleep apneaOropharyngolaryngeal structureVideofluoroscopic swallowing study

Identifiers

PMID38795279

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.