Evidence map›Paper›PMID 38795228›Full record

ArticleLasers in medical science2024

Settings and effectiveness of the revised probe compared to the original probe for micropulse transscleral cyclophotocoagulation.

Nicholas Hadjokas, Neelima Dosakayala, Samuel Alpert, Preethi Ganapathy, Robert Fechtner

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Outcomes of MicroPulseJournal of current glaucoma practice
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nicholas HadjokasSUNY Upstate Medical University Syracuse, Syracuse, NY, USA. nhadjokas@gmail.com.ORCID http://orcid.org/0000-0001-8646-0670
Neelima DosakayalaSUNY Upstate Medical University Syracuse, Syracuse, NY, USA.
Samuel AlpertSUNY Upstate Medical University Syracuse, Syracuse, NY, USA.
Preethi GanapathySUNY Upstate Medical University Syracuse, Syracuse, NY, USA.
Robert FechtnerSUNY Upstate Medical University Syracuse, Syracuse, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe goal of this study was to compare the settings and effectiveness of the original P3 and revised P3 probes for micropulse transscleral cyclophotocoagulation.

methodsThis retrospective cross sectional study includes a total of 56 patients with glaucoma who received micropulse transscleral cyclophotocoagulation. 32 patients received treatment with the original P3 probe and 24 received treatment with the revised P3 probe. Success was defined as a 20% reduction in intraocular pressure. Laser settings, pre-op and post-op intraocular pressures, and pre-op and post-op medications were assessed.

resultsA 20% IOP reduction was achieved in 50% of patients in the original probe vs. 58.3% in the revised probe at one month (P = 0.536) and 71.9% vs. 50% at three months (P = 0.094), respectively. The revised P3 probe used higher values of power (2500 mW vs. 2023 mW, P < 0.0001), total duration (217 s vs. 179 s, P < 0.0001), and energy (170 J vs. 113 J, P < 0.001). There was a significant decrease in IOP lowering meds with the original probe at one month (-0.9 +/- 1.5 vs. -0.0 +/- 0.7, P = 0.010), but this was not seen at three months.

conclusionsThere is no significant difference in IOP lowering effect between probes despite the revised probe using higher total energy. The original probe may be associated with fewer medications at 1 month, but not at 3 months. Further studies with longer follow up are needed to optimize the treatment parameters in order to maximize effectiveness while limiting side effects.

Indexed as

GlaucomaIntraocular PressureLaser CoagulationAdultAgedAged, 80 and overCiliary BodyCross-Sectional StudiesFemaleHumansMaleMiddle AgedRetrospective StudiesScleraTreatment OutcomeCiliary bodyCyclophotocoagulationGlaucomaLaser surgery

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.