Evidence map›Paper›PMID 38795180›Full record

ArticleCellular and molecular life sciences : CMLS2024

Targeting NG2 relieves the resistance of BRAF-mutant thyroid cancer cells to BRAF inhibitors.

Fang Sui, Guanjie Wang, Juan Liu, Mengmeng Yuan, Pu Chen, Yao Yao, Shaoqiang Zhang, Meiju Ji, Peng Hou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cellular and molecular life sciences : CMLS, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fang Sui *Department of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, 710061, P.R. China.
Guanjie Wang *Department of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, 710061, P.R. China.
Juan LiuDepartment of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, 710061, P.R. China.
Mengmeng YuanDepartment of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, 710061, P.R. China.
Pu ChenDepartment of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, 710061, P.R. China.
Yao YaoDepartment of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, 710061, P.R. China.
Shaoqiang ZhangDepartment of Otorhinolaryngology-Head and Neck Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, 710061, P.R. China.
Meiju JiCenter for Translational Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, 710061, P.R. China. mjji0409@163.com.
Peng HouDepartment of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, 710061, P.R. China. phou@xjtu.edu.cn.ORCID http://orcid.org/0000-0001-7010-7944

Funding

National Natural Science Foundation of China 82072949
6 · The paper itself

Abstract

BRAF

Indexed as

Drug Resistance, NeoplasmIndolesProtein Kinase InhibitorsProto-Oncogene Proteins B-rafSulfonamidesThyroid NeoplasmsAnimalsAntigensCell Line, TumorChondroitin Sulfate Proteoglycan 4Chondroitin Sulfate ProteoglycansHumansMembrane ProteinsMiceMutationPhenylurea CompoundsAntigensBRAF protein, humanChondroitin Sulfate Proteoglycan 4Chondroitin Sulfate ProteoglycansCSPG4 protein, humanIndoleslenvatinibMembrane ProteinsPhenylurea CompoundsPLX 4720Protein Kinase InhibitorsProteoglycansProto-Oncogene Proteins B-rafQuinolinesSorafenibSulfonamidesBRAF mutationsFeedback activationNG2Receptor tyrosine kinase (RTK)Thyroid cancer

Identifiers

PMID38795180
PMCPMC11127897

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.