Evidence map›Paper›PMID 38795015›Full record

ArticleInorganic chemistry2024

Interaction of MRI Contrast Agent [Gd(DOTA)]

Alexandre C Oliveira, Hugo A L Filipe, Carlos F G C Geraldes, Gregory A Voth, Maria João Moreno, Luís M S Loura

Abstract read
In one paragraph

Article in Inorganic chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexandre C OliveiraCoimbra Chemistry Centre, Institute of Molecular Sciences (CQC-IMS), 3004-535 Coimbra, Portugal.ORCID 0000-0001-7920-7773
Hugo A L FilipeCoimbra Chemistry Centre, Institute of Molecular Sciences (CQC-IMS), 3004-535 Coimbra, Portugal.ORCID 0000-0001-6935-4307
Carlos F G C GeraldesCoimbra Chemistry Centre, Institute of Molecular Sciences (CQC-IMS), 3004-535 Coimbra, Portugal.ORCID 0000-0002-0837-8329
Gregory A VothDepartment of Chemistry, Chicago Center for Theoretical Chemistry, James Franck Institute, and Institute for Biophysical Dynamics, University of Chicago, Chicago, Illinois 60637, United States.ORCID 0000-0002-3267-6748
Maria João MorenoCoimbra Chemistry Centre, Institute of Molecular Sciences (CQC-IMS), 3004-535 Coimbra, Portugal.ORCID 0000-0003-3076-9905
Luís M S LouraCoimbra Chemistry Centre, Institute of Molecular Sciences (CQC-IMS), 3004-535 Coimbra, Portugal.ORCID 0000-0002-1051-2312

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Contrast agents are important imaging probes in clinical MRI, allowing the identification of anatomic changes that otherwise would not be possible. Intensive research on the development of new contrast agents is being made to image specific pathological markers or sense local biochemical changes. The most widely used MRI contrast agents are based on gadolinium(III) complexes. Due to their very high charge density, they have low permeability through tight biological barriers such as the blood-brain barrier, hampering their application in the diagnosis of neurological disorders. In this study, we explore the interaction between the widely used contrast agent [Gd(DOTA)]

Indexed as

Contrast MediaLipid BilayersMagnetic Resonance ImagingMolecular Dynamics SimulationOrganometallic CompoundsHeterocyclic CompoundsPhosphatidylcholines1-palmitoyl-2-oleoylphosphatidylcholineContrast Mediagadolinium 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetateHeterocyclic CompoundsLipid BilayersOrganometallic CompoundsPhosphatidylcholines

Identifiers

PMID38795015
PMCPMC11186012

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.