Evidence map›Paper›PMID 38794960›Full record

ArticleEarly intervention in psychiatry2025

Validating cognitive screening in young people with first-episode psychosis: The CogScreen protocol.

Alexandra Stainton, Shayden Bryce, Audrey Rattray, Allie Pert, Isabel Zbukvic, Evangeline Fisher, Debbie Anderson, Stephen C Bowden, Symphony Chakma, Nicholas Cheng and 22 more

Abstract read
In one paragraph

Article in Early intervention in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Alexandra StaintonOrygen, Melbourne, Victoria, Australia.
Shayden BryceOrygen, Melbourne, Victoria, Australia.ORCID 0000-0001-6425-9861
Audrey RattrayOrygen, Melbourne, Victoria, Australia.
Allie PertOrygen, Melbourne, Victoria, Australia.ORCID 0009-0007-7793-4484
Isabel ZbukvicOrygen, Melbourne, Victoria, Australia.
Evangeline FisherOrygen, Melbourne, Victoria, Australia.
Debbie AndersonPrivate Practice, Brisbane, Queensland, Australia.
Stephen C BowdenMelbourne School of Psychological Sciences, The University of Melbourne, Parkville, Victoria, Australia.
Symphony ChakmaOrygen, Melbourne, Victoria, Australia.
Nicholas ChengOrygen, Melbourne, Victoria, Australia.
Scott ClarkDiscipline of Psychiatry, University of Adelaide, Adelaide, South Australia, Australia.
Caroline CrlenjakOrygen, Melbourne, Victoria, Australia.
Shona FranceyOrygen, Melbourne, Victoria, Australia.
Caroline GaoOrygen, Melbourne, Victoria, Australia.ORCID 0000-0002-0987-2759
Donna GeeOrygen, Melbourne, Victoria, Australia.
Elle GelokOrygen, Melbourne, Victoria, Australia.
Anthony HarrisSydney Medical School, University of Sydney, Sydney, New South Wales, Australia.
Lilianne HatfieldOrygen, Melbourne, Victoria, Australia.
Liza HopkinsAlfred Health, Melbourne, Victoria, Australia.ORCID 0000-0003-3383-2818
Candice JensenEarly Psychosis Team, Bondi Junction Community Health Centre, Bondi Junction, New South Wales, Australia.
Rachel MorellMindgardens Neuroscience Network, Sydney, New South Wales, Australia.
Chris O'HalloranAlfred Health, Melbourne, Victoria, Australia.
Scot PurdonDepartment of Psychiatry, University of Alberta, Edmonton, Alberta, Canada.
K Oliver SchubertDiscipline of Psychiatry, University of Adelaide, Adelaide, South Australia, Australia.
Alana ScullyEastern Suburbs Mental Health Service, SESLHD, Sydney, Australia.
Hejun TangOrygen, Melbourne, Victoria, Australia.
Adrian ThomasOrygen, Melbourne, Victoria, Australia.
Andrew ThompsonOrygen, Melbourne, Victoria, Australia.
Jacqueline UrenAlfred Health, Melbourne, Victoria, Australia.
Stephen J WoodOrygen, Melbourne, Victoria, Australia.
Wendi ZhaoOrygen, Melbourne, Victoria, Australia.
Kelly AllottOrygen, Melbourne, Victoria, Australia.ORCID 0000-0002-0640-4634

Funding

Australian Department of HealthMedical Research Future Fund MRFAR000034
6 · The paper itself

Abstract

aimCognitive impairments are a core feature of first-episode psychosis (FEP) and one of the strongest predictors of long-term psychosocial functioning. Cognition should be assessed and treated as part of routine clinical care for FEP. Cognitive screening offers the opportunity to rapidly identify and triage those in most need of cognitive support. However, there are currently no validated screening measures for young people with FEP. CogScreen is a hybrid effectiveness-implementation study which aims to evaluate the classification accuracy (relative to a neuropsychological assessment as a reference standard), test-retest reliability and acceptability of two cognitive screening tools in young people with FEP.

methodsParticipants will be 350 young people (aged 12-25) attending primary and specialist FEP treatment centres in three large metropolitan cities (Adelaide, Sydney, and Melbourne) in Australia. All participants will complete a cross-sectional assessment over two sessions including two cognitive screening tools (Screen for Cognitive Impairment in Psychiatry and Montreal Cognitive Assessment), a comprehensive neuropsychological assessment battery, psychiatric and neurodevelopmental assessments, and other supplementary clinical measures. To determine the test-retest reliability of the cognitive screening tools, a subset of 120 participants will repeat the screening measures two weeks later.

resultsThe protocol, rationale, and hypotheses for CogScreen are presented.

conclusionsCogScreen will provide empirical evidence for the validity and reliability of two cognitive screening tools when compared to a comprehensive neuropsychological assessment. The screening measures may later be incorporated into clinical practice to assist with rapid identification and treatment of cognitive deficits commonly experienced by young people with FEP.

Indexed as

Cognitive DysfunctionNeuropsychological TestsPsychotic DisordersAdolescentAdultAustraliaChildCross-Sectional StudiesFemaleHumansMaleReproducibility of ResultsYoung Adultadolescenceassessmentcognitionhybrid designschizophreniaSTARD guidelinesyouth mental health

Identifiers

PMID38794960
PMCPMC11730438

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.