Evidence map›Paper›PMID 38794942›Full record

Observational studyMedicina oral, patologia oral y cirugia bucal2024

Insights into incipient oral squamous cell carcinoma: a comprehensive south-american study.

C Saldivia-Siracusa, A-L Araújo, L-P Arboleda, T Abrantes, M-B Pinto, N Mendonça, K Cordero-Torres, G Gilligan, E Piemonte, R Panico and 2 more

Abstract readObservational StudyMulticenter Study
In one paragraph

Observational study in Medicina oral, patologia oral y cirugia bucal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

C Saldivia-SiracusaOral Diagnosis Department Piracicaba Dental School, UNICAMP Av. Limeira, no 901, Areão, Piracicaba Postal code: 13414- 903. São Paulo, Brazil alan@unicamp.br.
A-L Araújo
L-P Arboleda
T Abrantes
M-B Pinto
N Mendonça
K Cordero-Torres
G Gilligan
E Piemonte
R Panico
F De-Abreu-Álves
M Villaroel-Dorrego

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo describe demographic and clinicopathological aspects of a South-American cohort of incipient oral squamous cell carcinoma patients. MATERIAL AND

methodsA cross-sectional, observational study was performed to assess demographic and clinicopathological characteristics of incipient oral squamous cell carcinoma patients from 6 South-American institutions.

resultsOne hundred and seven patients within the histopathological spectrum of incipient oral squamous cell carcinoma (in-situ and microinvasive) were included. Fifty-eight (54.2%) patients were men with a mean age of 60.69 years. Forty-nine (45.8%) and thirty-nine (36.5%) patients had history of tobacco and alcohol use, respectively. Clinically, most of the lesions were plaques (82.2%), ≥ 2 cm in extension (72%), affecting the lateral border of the tongue (55.1%), and soft palate (12.1%) with a mixed (white and red) appearance. Eighty-two (76.7%) lesions were predominantly white and 25 (23.3%) predominantly red.

conclusionsTo the best of our knowledge, this is the largest cohort of incipient oral squamous cell carcinoma patients, which raises awareness of clinicians' inspection acuteness by demonstrating the most frequent clinical aspects of this disease, potentially improving oral cancer secondary prevention strategies.

Indexed as

Carcinoma, Squamous CellMouth NeoplasmsAdultAgedAged, 80 and overCross-Sectional StudiesFemaleHumansMaleMiddle AgedSouth America

Identifiers

PMID38794942
PMCPMC11249374

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.