Evidence map›Paper›PMID 38794935›Full record

Observational studyMedicina oral, patologia oral y cirugia bucal2024

Tooth loss in breast cancer patients: A comparison between tamoxifen-treated and non-treated patients.

J-J Julca-Baltazar, A-S Asmat-Abanto, A-R Pantoja-Lázaro, A-P Gorritti-Rubio, C-A Minchón-Medina

Abstract readObservational StudyComparative Study
In one paragraph

Observational study in Medicina oral, patologia oral y cirugia bucal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

J-J Julca-BaltazarAmerica Sur Avenue N° 3145 Monserrate Neighborhood Trujillo, 13008, Peru aasmat.abanto@gmail.com.
A-S Asmat-Abanto
A-R Pantoja-Lázaro
A-P Gorritti-Rubio
C-A Minchón-Medina

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTooth loss (TL) affects quality of life and general health. The literature suggesting that tamoxifen treatment in patients with breast cancer (BC) could be associated with alterations in oral health, increasing the risk of TL, is still scarce. This work aimed to determine the relationship between TL and tamoxifen consumption in patients with BC. MATERIAL AND

methodsThis cross-sectional observational study was carried out from July to September 2023 in the medical oncology services of the "Virgen de la Puerta" - ESSALUD High Complexity Hospital and "Dr. Luis Pinillos Ganoza" - IREN Norte - Regional Institute of Neoplastic Diseases, in Trujillo - Peru. Overall, 200 adult patients diagnosed with BC were evaluated, of which 100 consumed tamoxifen and 100 did not. Inter- and intra-rater reliability was determined with respect to TL, resulting in intra-class correlation values RHO = 0.971 and interclass RHO = 0.938. The oncologist of the corresponding service performed BC diagnosis and stage. Poisson regression was used to analyze results with a significance level of p<0.05.

resultsNo relationship was found between TL and tamoxifen consumption in patients with breast cancer (p= 0.221); however, greater TL was observed in women who consumed tamoxifen for more than one year compared to those who did not use it (p=0.025) and in older adult women compared to young women (p=0.030).

conclusionsThere is a relationship between TL and time of use of tamoxifen in patients with BC, concluding that patients who consumed tamoxifen for more than one year had greater TL than those who did not. Furthermore, no relationship was found between TL and cancer stages, but there was greater TL in older adult patients and also in those who consumed tamoxifen and did not receive chemotherapy or radiotherapy.

Indexed as

Antineoplastic Agents, HormonalBreast NeoplasmsTamoxifenTooth LossAdultAgedCross-Sectional StudiesFemaleHumansMiddle AgedAntineoplastic Agents, HormonalTamoxifen

Identifiers

PMID38794935
PMCPMC11249377

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.