Evidence map›Paper›PMID 38794736›Full record

ArticleNutrients2024

Low-Protein Diet in Elderly Patients with Chronic Kidney Disease Stage 4 and 5 in Conservative Management: Focus on Sarcopenia Development.

Francesca K Martino, Alessandra Zattarin, Chiara Cinquini, Silvia Toniazzo, Francesco Francini Pesenti, Lucia Federica Stefanelli, Martina Cacciapuoti, Elisabetta Bettin, Lorenzo A Calò, Paolo Spinella

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In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Francesca K MartinoNephrology, Dialysis and Transplantation Unit, Department of Medicine (DIMED), University of Padova, 35128 Padua, Italy.ORCID 0000-0002-2402-9276
Alessandra ZattarinDepartment of Medicine (DIMED), Clinical Nutrition, University of Padua, 35128 Padua, Italy.
Chiara CinquiniDepartment of Medicine (DIMED), Clinical Nutrition, University of Padua, 35128 Padua, Italy.
Silvia ToniazzoDepartment of Medicine (DIMED), Clinical Nutrition, University of Padua, 35128 Padua, Italy.
Francesco Francini PesentiDepartment of Medicine (DIMED), Clinical Nutrition, University of Padua, 35128 Padua, Italy.
Lucia Federica StefanelliNephrology, Dialysis and Transplantation Unit, Department of Medicine (DIMED), University of Padova, 35128 Padua, Italy.
Martina CacciapuotiNephrology, Dialysis and Transplantation Unit, Department of Medicine (DIMED), University of Padova, 35128 Padua, Italy.
Elisabetta BettinNephrology, Dialysis and Transplantation Unit, Department of Medicine (DIMED), University of Padova, 35128 Padua, Italy.
Lorenzo A CalòNephrology, Dialysis and Transplantation Unit, Department of Medicine (DIMED), University of Padova, 35128 Padua, Italy.ORCID 0000-0002-7534-0128
Paolo SpinellaDepartment of Medicine (DIMED), Clinical Nutrition, University of Padua, 35128 Padua, Italy.

Funding

grant DOR n. 2397544/2023 from the University of Padova to Lorenzo Calò 2397544/2023University of Padova to Paolo Spinella DOR n 2344749/23 2344749/23
6 · The paper itself

Abstract

introductionChronic kidney disease is a degenerative and increasingly prevalent condition that includes metabolic abnormalities and is associated with a higher risk of sarcopenia. The conservative approach points primarily to controlling metabolic issues and reducing the risk of malnutrition and sarcopenia, slowing the progression of kidney disease. The present study aims to evaluate the effect of a low-protein diet on malnutrition and sarcopenia.

methodsA total of 45 patients (33 male and 12 female) aged over 70 with chronic kidney disease stage 4-5 in conservative management were considered. All patients had a dietary assessment and prescription of personalized low-protein dietary plans (≤0.6 g protein/kg) and a follow-up control between 4 and 6 months. In preliminary and follow-up evaluations, anthropometric data, blood examinations, body composition results, muscle strength, physical performance, and a 3-day food diary were collected.

resultsIn the follow-up period, a significant weight loss (

conclusionsProviding a personalized low-protein diet led to significant benefits in a short period without worsening the patient's nutritional status.

Indexed as

Diet, Protein-RestrictedRenal Insufficiency, ChronicSarcopeniaAgedAged, 80 and overBody CompositionBody Mass IndexConservative TreatmentFemaleHumansMaleMalnutritionMuscle StrengthNutritional StatusWeight Losschronic kidney diseasedietary interventionslow protein dietsarcopenia

Identifiers

PMID38794736
PMCPMC11123811

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.