Evidence map›Paper›PMID 38794668›Full record

ArticleNutrients2024

Evaluation of Gastroprotective Activity of the Methanolic Extract of

Ismael Aureliano Rosa Júnior, Dionys de Souza Almeida, Hamilton Barbosa Napolitano, Josana de Castro Peixoto, Lucimar Pinheiro Rosseto, Emerith Mayra Hungria Pinto, Lucas Danilo Dias, James Oluwagbamigbe Fajemiroye, Elson Alves Costa, Rodolfo P Vieira and 1 more

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Phytochemical Profiling and Antioxidant Activity ofPharmaceuticals (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ismael Aureliano Rosa JúniorPostgraduate Program in Pharmaceutical Sciences, Pharmacology and Therapeutics, Evangelical University of Goiás-Unievangélica, University Avenue Km 3,5, Anápolis 75083-515, GO, Brazil.
Dionys de Souza AlmeidaInstitute of Biological Sciences, Department of Pharmacology, Federal University of Goiás, Campus Samambaia, Campus Street, Goiânia 74001-97, GO, Brazil.
Hamilton Barbosa NapolitanoPostgraduate Program in Pharmaceutical Sciences, Pharmacology and Therapeutics, Evangelical University of Goiás-Unievangélica, University Avenue Km 3,5, Anápolis 75083-515, GO, Brazil.
Josana de Castro PeixotoPostgraduate Program in Pharmaceutical Sciences, Pharmacology and Therapeutics, Evangelical University of Goiás-Unievangélica, University Avenue Km 3,5, Anápolis 75083-515, GO, Brazil.
Lucimar Pinheiro RossetoPostgraduate Program in Pharmaceutical Sciences, Pharmacology and Therapeutics, Evangelical University of Goiás-Unievangélica, University Avenue Km 3,5, Anápolis 75083-515, GO, Brazil.
Emerith Mayra Hungria PintoPostgraduate Program in Pharmaceutical Sciences, Pharmacology and Therapeutics, Evangelical University of Goiás-Unievangélica, University Avenue Km 3,5, Anápolis 75083-515, GO, Brazil.
Lucas Danilo DiasPostgraduate Program in Pharmaceutical Sciences, Pharmacology and Therapeutics, Evangelical University of Goiás-Unievangélica, University Avenue Km 3,5, Anápolis 75083-515, GO, Brazil.ORCID 0000-0003-2858-7539
James Oluwagbamigbe FajemiroyePostgraduate Program in Pharmaceutical Sciences, Pharmacology and Therapeutics, Evangelical University of Goiás-Unievangélica, University Avenue Km 3,5, Anápolis 75083-515, GO, Brazil.ORCID 0000-0001-7440-7581
Elson Alves CostaInstitute of Biological Sciences, Department of Pharmacology, Federal University of Goiás, Campus Samambaia, Campus Street, Goiânia 74001-97, GO, Brazil.ORCID 0000-0003-1996-0901
Rodolfo P VieiraPostgraduate Program in Pharmaceutical Sciences, Pharmacology and Therapeutics, Evangelical University of Goiás-Unievangélica, University Avenue Km 3,5, Anápolis 75083-515, GO, Brazil.ORCID 0000-0001-6379-1143
José Luis Rodrigues MartinsPostgraduate Program in Pharmaceutical Sciences, Pharmacology and Therapeutics, Evangelical University of Goiás-Unievangélica, University Avenue Km 3,5, Anápolis 75083-515, GO, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction

aimsTo investigate the gastroprotective activity of the methanol extract of the leaves of MATERIALS AND

methodsThe adult leaves of

resultsMEJP (250, 500 and 1000 mg/kg p.o.) demonstrated gastroprotective activity, with levels of protection of 45.65%, 44.80% and 40.22%, respectively, compared to the control (vehicle). Compared with cimetidine (48.29%), MEJP showed similar gastroprotective activity.

conclusionsThis study demonstrated the gastroprotective activity of MEJP and contributes to validate the traditional use the species for gastric disorders and provides a pharmacological basis for its clinical potential.

Indexed as

Plant ExtractsPlant LeavesStomach UlcerAcanthaceaeAnimalsAnti-Ulcer AgentsBrazilCimetidineDisease Models, AnimalGastric MucosaIndomethacinJusticiaMaleMethanolMiceAnti-Ulcer AgentsCimetidineIndomethacinMethanolPlant ExtractsAcanthaceagastric ulcergastroprotective activityJusticia pectoralis Jacq.methanolic extract

Identifiers

PMID38794668
PMCPMC11123913

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.