Evidence map›Paper›PMID 38794598›Full record

ReviewPolymers2024

Polyglycerol Sebacate Elastomer: A Critical Overview of Synthetic Methods and Characterisation Techniques.

Mariella Rosalia, Davide Rubes, Massimo Serra, Ida Genta, Rossella Dorati, Bice Conti

Abstract readReview
In one paragraph

Review in Polymers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mariella RosaliaDepartment of Drug Science, University of Pavia, Via Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0002-3677-3393
Davide RubesDepartment of Drug Science, University of Pavia, Via Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0002-8557-4577
Massimo SerraDepartment of Drug Science, University of Pavia, Via Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0002-6724-4355
Ida GentaDepartment of Drug Science, University of Pavia, Via Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0001-5710-0588
Rossella DoratiDepartment of Drug Science, University of Pavia, Via Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0001-5774-9547
Bice ContiDepartment of Drug Science, University of Pavia, Via Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0002-0034-2815

Funding

NextGeneration EU-MUR PNRR PE00000007, INF-ACT
6 · The paper itself

Abstract

Poly (glycerol sebacate) is a widely studied elastomeric copolymer obtained from the polycondensation of two bioresorbable monomers, glycerol and sebacic acid. Due to its biocompatibility and the possibility to tailor its biodegradability rate and mechanical properties, PGS has gained lots of interest in the last two decades, especially in the soft tissue engineering field. Different synthetic approaches have been proposed, ranging from classic thermal polyesterification and curing to microwave-assisted organic synthesis, UV crosslinking and enzymatic catalysis. Each technique, characterized by its advantages and disadvantages, can be tailored by controlling the crosslinking density, which depends on specific synthetic parameters. In this work, classic and alternative synthetic methods, as well as characterisation and tailoring techniques, are critically reviewed with the aim to provide a valuable tool for the reproducible and customized production of PGS for tissue engineering applications.

Indexed as

characterisationpolyglycerol sebacatepolymer tailoringsynthesis

Identifiers

PMID38794598
PMCPMC11124930

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.