Evidence map›Paper›PMID 38794563›Full record

ArticlePolymers2024

Simple Electrospinning Method for Biocompatible Polycaprolactone β-Carotene Scaffolds: Advantages and Limitations.

Orion Yoshikawa, Valentina Basoli, Francesco Boschetto, Alfredo Rondinella, Alex Lanzutti, Wenliang Zhu, Enrico Greco, Florian Markus Thieringer, Huaizhong Xu, Elia Marin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Orion YoshikawaCeramic Physics Laboratory, Faculty of Materials Science and Engineering, Kyoto Institute of Technology, Sakyo-ku, Matsugasaki, Kyoto 606-8585, Japan.
Valentina BasoliMedical Additive Manufacturing Research Group (Swiss MAM), Department of Biomedical Engineering, University of Basel, Hegenheimermattweg 167C, 4123 Allschwil, Switzerland.ORCID 0000-0002-4703-7308
Francesco BoschettoCenter for Excellence in Hip, Scottish Rite for Children, Dallas, TX 75219, USA.ORCID 0000-0002-1603-9597
Alfredo RondinellaPolytechnic Department of Engineering and Architecture, University of Udine, 33100 Udine, Italy.
Alex LanzuttiPolytechnic Department of Engineering and Architecture, University of Udine, 33100 Udine, Italy.ORCID 0000-0002-3256-3516
Wenliang ZhuCeramic Physics Laboratory, Faculty of Materials Science and Engineering, Kyoto Institute of Technology, Sakyo-ku, Matsugasaki, Kyoto 606-8585, Japan.ORCID 0000-0001-7532-9714
Enrico GrecoDepartment of Chemical and Pharmaceutical Sciences, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0003-1564-4661
Florian Markus ThieringerMedical Additive Manufacturing Research Group (Swiss MAM), Department of Biomedical Engineering, University of Basel, Hegenheimermattweg 167C, 4123 Allschwil, Switzerland.ORCID 0000-0003-3035-9308
Huaizhong XuDepartment of Biobased Materials Science, Kyoto Institute of Technology, Sakyo-ku, Matsugasaki, Kyoto 606-8585, Japan.ORCID 0000-0001-7291-1936
Elia MarinPolytechnic Department of Engineering and Architecture, University of Udine, 33100 Udine, Italy.ORCID 0000-0002-0981-7821

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, electrospun scaffolds were fabricated using polycaprolactone (PCL) loaded with varying concentrations of β-carotene (1.2%, 2.4%, and 3.6%) via the electrospinning technique. The electrospinning process involved the melting of PCL in acetic acid, followed by the incorporation of β-carotene powder under constant stirring. Raman spectroscopy revealed a homogeneous distribution of β-carotene within the PCL matrix. However, the β-carotene appeared in particulate form, rather than being dissolved and blended with the PCL matrix, a result also confirmed by thermogravimetric analysis. Additionally, X-ray diffraction analysis indicated a decrease in crystallinity with increasing β-carotene concentration. Mechanical testing of the scaffolds demonstrated an increase in ultimate strain, accompanied by a reduction in ultimate stress, indicating a potential plasticizing effect. Moreover, antimicrobial assays revealed a marginal antibacterial effect against

Indexed as

antibacterialcellular proliferationelectrospinningpolycaprolactonescaffoldstissue engineeringβ-carotene

Identifiers

PMID38794563
PMCPMC11125378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.