ArticlePolymers2024
In Vitro Cytotoxic and Inflammatory Response of Gingival Fibroblasts and Oral Mucosal Keratinocytes to 3D Printed Oral Devices.
Article in Polymers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Clear Aligners as a Prescribed Source of Unmeasured Intra-Oral Micro- and Nanoplastic Exposure: Release Mechanisms, Human Evidence, Salivary Biomonitoring and the EU Regulatory Context.Materials (Basel, Switzerland) · 2026Review
- In Vitro Cytotoxicity of Three Dimethacrylate-Based Photopolymer Resins for 3D-Printed Dental Restorations: A Qualitative Morphological Screening on Human Fibroblasts.Journal of functional biomaterials · 2026Article
- Towards standardizing cytotoxicity testing of 3D-printed orthodontic aligners and retainers: a scoping review.Progress in orthodontics · 2026Article
- Bioactive Assessment of MMA-Based Dental Materials: Molecular Docking and Network Topology Analysis of Stress-Regulated Survival, Apoptosis, and Mechanotransduction Pathways.Current issues in molecular biology · 2026Article
- Biocompatibility and Cell Death Mechanisms Induced by PMMA-Based Dental Materials in Gingival Fibroblasts and OECM-1 Tumor Cells.Dentistry journal · 2026Article
- Biological Safety of 3D Printing Materials Based on Acrylic Resins Used in Dentistry: Narrative Review.Materials (Basel, Switzerland) · 2026Review
- Evaluation of Post-Processing Time's Influence on Biocompatibility of 3D-Printed Denture Base Resins.Journal of functional biomaterials · 2026Article
- In Vitro Study Regarding Cytotoxic and Inflammatory Response of Gingival Fibroblasts to a 3D-Printed Resin for Denture Bases.Journal of functional biomaterials · 2025Article
- Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The purpose of this study was to examine the biocompatibility of 3D printed materials used for additive manufacturing of rigid and flexible oral devices. Oral splints were produced and finished from six printable resins (pairs of rigid/flexible materials: KeySplint Hard [KR], KeySplint Soft [KF], V-Print Splint [VR], V-Print Splint Comfort [VF], NextDent Ortho Rigid [NR], NextDent Ortho Flex [NF]), and two types of PMMA blocks for subtractive manufacturing (Tizian Blank PMMA [TR], Tizian Flex Splint Comfort [TF]) as controls. The specimens were eluted in a cell culture medium for 7d. Human gingival fibroblasts (hGF-1) and human oral mucosal keratinocytes (hOK) were exposed to the eluates for 24 h. Cell viability, glutathione levels, apoptosis, necrosis, the cellular inflammatory response (IL-6 and PGE
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.