Evidence map›Paper›PMID 38794329›Full record

ReviewPharmaceutics2024

Self-Immolative Domino Dendrimers as Anticancer-Drug Delivery Systems: A Review.

Karolina Kędra, Ewa Oledzka, Marcin Sobczak

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Karolina KędraInstitute of Physical Chemistry, Polish Academy of Sciences, 44/52 Kasprzaka Str., 01-224 Warsaw, Poland.ORCID 0000-0002-3696-1618
Ewa OledzkaFaculty of Pharmacy, Department of Pharmaceutical Chemistry and Biomaterials, Medical University of Warsaw, 1 Banacha Str., 02-097 Warsaw, Poland.ORCID 0000-0003-0660-3315
Marcin SobczakFaculty of Pharmacy, Department of Pharmaceutical Chemistry and Biomaterials, Medical University of Warsaw, 1 Banacha Str., 02-097 Warsaw, Poland.ORCID 0000-0002-7362-8881

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Worldwide cancer statistics have indicated about 20 million new cancer cases and over 10 million deaths in 2022 (according to data from the International Agency for Research on Cancer). One of the leading cancer treatment strategies is chemotherapy, using innovative drug delivery systems (DDSs). Self-immolative domino dendrimers (SIDendr) for triggered anti-cancer drugs appear to be a promising type of DDSs. The present review provides an up-to-date survey on the contemporary advancements in the field of SIDendr-based anti-cancer drug delivery systems (SIDendr-ac-DDSs) through an exhaustive analysis of the discovery and application of these materials in improving the pharmacological effectiveness of both novel and old drugs. In addition, this article discusses the designing, chemical structure, and targeting techniques, as well as the properties, of several SIDendr-based DDSs. Approaches for this type of targeted DDSs for anti-cancer drug release under a range of stimuli are also explored.

Indexed as

anti-cancer drug delivery systemsbiomedical dendrimerscontrolled drug releasedrug delivery systemsself-immolative domino dendrimers

Identifiers

PMID38794329
PMCPMC11125333

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.