Evidence map›Paper›PMID 38794104›Full record

ArticleSensors (Basel, Switzerland)2024

Silicon Microring Resonator Biosensor for Detection of Nucleocapsid Protein of SARS-CoV-2.

Yusuke Uchida, Taro Arakawa, Akio Higo, Yuhei Ishizaka

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Functionalized Optical Microcavities for Sensing Applications.Nanomaterials (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yusuke UchidaGraduate School of Engineering, Yokohama National University, 79-5 Tokiwada, Hodogaya-ku, Yokohama 240-8501, Japan.
Taro ArakawaGraduate School of Engineering, Yokohama National University, 79-5 Tokiwada, Hodogaya-ku, Yokohama 240-8501, Japan.ORCID 0000-0001-9474-7399
Akio HigoSystem Design Lab, School of Engineering, The University of Tokyo, 2-11-16, Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan.ORCID 0000-0002-4595-0929
Yuhei IshizakaDepartment of Science and Engineering, Kanto Gakuin University, 1-50-1 Mutsuura-higashi, Kanazawa-ku, Yokohama 236-8501, Japan.

Funding

Ministry of Education, Culture, Sports, Science and Technology 21H01841
6 · The paper itself

Abstract

A high-sensitivity silicon microring (Si MRR) optical biosensor for detecting the nucleocapsid protein of SARS-CoV-2 is proposed and demonstrated. In the proposed biosensor, the surface of a Si MRR waveguide is modified with antibodies, and the target protein is detected by measuring a resonant wavelength shift of the MRR caused by the selective adsorption of the protein to the surface of the waveguide. A Si MRR is fabricated on a silicon-on-insulator substrate using a CMOS-compatible fabrication process. The quality factor of the MRR is approximately 20,000. The resonant wavelength shift of the MRR and the detection limit for the environmental refractive index change are evaluated to be 89 nm/refractive index unit (RIU) and 10

Indexed as

Biosensing TechniquesCoronavirus Nucleocapsid ProteinsSARS-CoV-2SiliconCOVID-19HumansLimit of DetectionPhosphoproteinsCoronavirus Nucleocapsid Proteinsnucleocapsid phosphoprotein, SARS-CoV-2PhosphoproteinsSiliconInG antibodynucleocapsid proteinoptical biosensingsilicon microring resonatorSi-tagged protein

Identifiers

PMID38794104
PMCPMC11125905

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.