Evidence map›Paper›PMID 38793811›Full record

ArticleVaccines2024

Healthcare Providers' and Pregnant People's Preferences for a Preventive to Protect Infants from Serious Illness Due to Respiratory Syncytial Virus.

Kathleen M Beusterien, Amy W Law, Martine C Maculaitis, Oliver Will, Lewis Kopenhafer, Patrick Olsen, Brett Hauber, Jeffrey T Vietri, Joseph C Cappelleri, Joshua R Coulter and 1 more

Abstract read
In one paragraph

Article in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Observational
  5. Article
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  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kathleen M BeusterienOracle Life Sciences, Austin, TX 78741, USA.
Amy W LawPfizer Inc., New York, NY 10001, USA.
Martine C MaculaitisOracle Life Sciences, Austin, TX 78741, USA.ORCID 0000-0001-8388-5315
Oliver WillOracle Life Sciences, Austin, TX 78741, USA.
Lewis KopenhaferOracle Life Sciences, Austin, TX 78741, USA.
Patrick OlsenOracle Life Sciences, Austin, TX 78741, USA.
Brett HauberPfizer Inc., New York, NY 10001, USA.ORCID 0000-0003-3129-7268
Jeffrey T VietriPfizer Inc., Collegeville, PA 19426, USA.
Joseph C CappelleriPfizer Inc., Groton, CT 06340, USA.
Joshua R CoulterPfizer Inc., New York, NY 10001, USA.
Kimberly M SheaPfizer Inc., New York, NY 10001, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We assessed the impact of respiratory syncytial virus (RSV) preventive characteristics on the intentions of pregnant people and healthcare providers (HCPs) to protect infants with a maternal vaccine or monoclonal antibodies (mAbs). Pregnant people and HCPs who treated pregnant people and/or infants were recruited via convenience sample from a general research panel to complete a cross-sectional, web-based survey, including a discrete choice experiment (DCE) wherein respondents chose between hypothetical RSV preventive profiles varying on five attributes (effectiveness, preventive type [maternal vaccine vs. mAb], injection recipient/timing, type of medical visit required to receive the injection, and duration of protection during RSV season) and a no-preventive option. A best-worst scaling (BWS) exercise was included to explore the impact of additional attributes on preventive preferences. Data were collected between October and November 2022. Attribute-level preference weights and relative importance (RI) were estimated. Overall, 992 pregnant people and 310 HCPs participated. A preventive (vs. none) was chosen 89.2% (pregnant people) and 96.0% (HCPs) of the time (DCE). Effectiveness was most important to preventive choice for pregnant people (RI = 48.0%) and HCPs (RI = 41.7%); all else equal, pregnant people (RI = 5.5%) and HCPs (RI = 7.2%) preferred the maternal vaccine over mAbs, although preventive type had limited influence on choice. Longer protection, protection starting at birth or the beginning of RSV season, and use for both pre-term and full-term babies were ranked highest in importance (BWS). Pregnant people and HCPs strongly preferred a preventive to protect infants against RSV (vs. none), underscoring the need to incorporate RSV preventives into routine care.

Indexed as

healthcare providersmaternal vaccinationmonoclonal antibodiespregnant peoplerespiratory syncytial virusstakeholder preferences

Identifiers

PMID38793811
PMCPMC11125959

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.