Evidence map›Paper›PMID 38793809›Full record

ArticleVaccines2024

Accuracy of Anti-SARS-CoV-2 Antibody in Comparison with Surrogate Viral Neutralization Test in Persons Living with HIV, Systemic Lupus Erythematosus, and Chronic Kidney Disease.

Marita Restie Tiara, Chrisan Bimo Prayuda, Tara Titian Maulidya, Hofiya Djauhari, Dadang Suhendar, Rudi Wisaksana, Laniyati Hamijoyo, Rudi Supriyadi, Agnes Rengga Indrati, Bachti Alisjahbana

Abstract read
In one paragraph

Article in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marita Restie TiaraResearch Center for Care and Control of Infectious Disease, Universitas Padjadjaran, Bandung 40161, Indonesia.
Chrisan Bimo PrayudaResearch Center for Care and Control of Infectious Disease, Universitas Padjadjaran, Bandung 40161, Indonesia.ORCID 0009-0009-4736-901X
Tara Titian MaulidyaResearch Center for Care and Control of Infectious Disease, Universitas Padjadjaran, Bandung 40161, Indonesia.
Hofiya DjauhariResearch Center for Care and Control of Infectious Disease, Universitas Padjadjaran, Bandung 40161, Indonesia.
Dadang SuhendarResearch Center for Applied Microbiology, National Research and Innovation Agency (BRIN), KST Soekarno, Cibinong, Jl. Raya Jakarta-Bogor KM 46, Cibinong 16911, Indonesia.
Rudi WisaksanaResearch Center for Care and Control of Infectious Disease, Universitas Padjadjaran, Bandung 40161, Indonesia.
Laniyati HamijoyoRheumatology Division, Department of Internal Medicine, Hasan Sadikin Hospital, Faculty of Medicine, Universitas Padjadjaran, Bandung 40161, Indonesia.
Rudi SupriyadiNephrology and Hypertension Division, Internal Medicine Department, Hasan Sadikin Hospital, Faculty of Medicine, Universitas Padjadjaran, Bandung 40161, Indonesia.
Agnes Rengga IndratiResearch Center for Care and Control of Infectious Disease, Universitas Padjadjaran, Bandung 40161, Indonesia.ORCID 0000-0003-3923-9767
Bachti AlisjahbanaResearch Center for Care and Control of Infectious Disease, Universitas Padjadjaran, Bandung 40161, Indonesia.ORCID 0000-0003-3745-8229

Funding

The Indonesian Agency for Research and Innovation (BRIN) 123
6 · The paper itself

Abstract

The presence of the anti-SARS-CoV-2-RBD antibody (anti-RBD) prevents severe COVID-19. We aimed to determine the accuracy of a point-of-care anti-RBD testing implemented in persons living with HIV (PLWH), systemic lupus erythematosus (SLE), and chronic kidney disease (CKD). We enrolled 182 non-comorbid subjects and 335 comorbid subjects (PLWH, SLE, CKD) to test the anti-RBD assay compared to the surrogate viral neutralization test (sVNT) as the reference test. We performed linear correlation analysis between anti-RBD and sVNT, along with an ROC analysis to ascertain the anti-RBD cutoff at 30%, 60%, and 90% inhibition of sVNT, to calculate accuracy. The correlations between anti-RBD and sVNT among all groups were excellent, with R = 0.7903, R = 0.7843, and R = 0.8153 among the non-comorbid, SLE, and CKD groups, respectively, and with significantly higher correlation among the PLWH group (R = 0.8877;

Indexed as

antibodyCOVID-19immunoassayvaccination

Identifiers

PMID38793809
PMCPMC11125822

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.