Evidence map›Paper›PMID 38793739›Full record

ArticleVaccines2024

Virological Traits of the SARS-CoV-2 BA.2.87.1 Lineage.

Lu Zhang, Alexandra Dopfer-Jablonka, Inga Nehlmeier, Amy Kempf, Luise Graichen, Noemí Calderón Hampel, Anne Cossmann, Metodi V Stankov, Gema Morillas Ramos, Sebastian R Schulz and 4 more

Abstract read
In one paragraph

Article in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Lu ZhangInfection Biology Unit, German Primate Center-Leibniz Institute for Primate Research, 37077 Göttingen, Germany.
Alexandra Dopfer-JablonkaDepartment of Rheumatology and Immunology, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0001-7129-100X
Inga NehlmeierInfection Biology Unit, German Primate Center-Leibniz Institute for Primate Research, 37077 Göttingen, Germany.
Amy KempfInfection Biology Unit, German Primate Center-Leibniz Institute for Primate Research, 37077 Göttingen, Germany.
Luise GraichenInfection Biology Unit, German Primate Center-Leibniz Institute for Primate Research, 37077 Göttingen, Germany.
Noemí Calderón HampelDepartment of Rheumatology and Immunology, Hannover Medical School, 30625 Hannover, Germany.
Anne CossmannDepartment of Rheumatology and Immunology, Hannover Medical School, 30625 Hannover, Germany.
Metodi V StankovDepartment of Rheumatology and Immunology, Hannover Medical School, 30625 Hannover, Germany.
Gema Morillas RamosDepartment of Rheumatology and Immunology, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0002-4835-5172
Sebastian R SchulzDivision of Molecular Immunology, Department of Internal Medicine 3, Friedrich-Alexander University of Erlangen-Nürnberg, 91054 Erlangen, Germany.ORCID 0000-0001-6554-3346
Hans-Martin JäckDivision of Molecular Immunology, Department of Internal Medicine 3, Friedrich-Alexander University of Erlangen-Nürnberg, 91054 Erlangen, Germany.ORCID 0000-0002-6332-8463
Georg M N BehrensDepartment of Rheumatology and Immunology, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0003-3111-621X
Stefan PöhlmannInfection Biology Unit, German Primate Center-Leibniz Institute for Primate Research, 37077 Göttingen, Germany.ORCID 0000-0001-6086-9136
Markus HoffmannInfection Biology Unit, German Primate Center-Leibniz Institute for Primate Research, 37077 Göttingen, Germany.ORCID 0000-0003-4603-7696

Funding

Bavarian Research Foundation Project CORAdBavarian State Ministry for Science and Art RTG1660China Scholarship Council 202006270031Deutsche Forschungsgemeinschaft PO 716/11-1Deutsche Forschungsgemeinschaft TRR130European Commission 101057100European Union ZAM5-87006761European Union ZW7-85151373Federal Ministry of Education and Research 01KI2043Federal Ministry of Education and Research NaFoUniMedCovid19-COVIM: 01KX2021German Center for Infection Research 80018019238Kastner Foundation n/aNiedersächsisches Ministerium für Wissenschaft und Kultur 14-76103-184 (10FF22)Niedersächsisches Ministerium für Wissenschaft und Kultur 14-76103-184 (4LZF23)Niedersächsisches Ministerium für Wissenschaft und Kultur 14-76103-184 (6FF22)Niedersächsisches Ministerium für Wissenschaft und Kultur 14-76103-184 (7FF22)
6 · The paper itself

Abstract

Transmissibility and immune evasion of the recently emerged, highly mutated SARS-CoV-2 BA.2.87.1 are unknown. Here, we report that BA.2.87.1 efficiently enters human cells but is more sensitive to antibody-mediated neutralization than the currently dominating JN.1 variant. Acquisition of adaptive mutations might thus be needed for efficient spread in the population.

Indexed as

ACE2 bindingantibody evasionBA.2.87.1host cell entrySARS-CoV-2spike protein

Identifiers

PMID38793739
PMCPMC11125805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.