Evidence map›Paper›PMID 38793665›Full record

ReviewViruses2024

Mpox (Monkeypox) Virus and Its Co-Infection with HIV, Sexually Transmitted Infections, or Bacterial Superinfections: Double Whammy or a New Prime Culprit?

Benjamin M Liu, Natella Y Rakhmanina, Zhilong Yang, Michael I Bukrinsky

Abstract readReview
In one paragraph

Review in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. High rates of Treponema pallidum, Neisseria gonorrhoeae, Chlamydia trachomatis, or Trichomonas vaginalis co-infection in people with HIV: a systematic review and meta-analysis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
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  9. Evaluation of a Novel Multiplex PCR Assay for Vesicular Viruses.International journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Benjamin M LiuDivision of Pathology and Laboratory Medicine, Children's National Hospital, Washington, DC 20010, USA.ORCID 0000-0003-1225-9936
Natella Y RakhmaninaDepartment of Pediatrics, George Washington University School of Medicine and Health Sciences, Washington, DC 20010, USA.ORCID 0000-0002-2246-4581
Zhilong YangDepartment of Veterinary Pathobiology, School of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.
Michael I BukrinskyDepartment of Microbiology, Immunology & Tropical Medicine, George Washington University School of Medicine and Health Sciences, Washington, DC 20037, USA.ORCID 0000-0002-8593-0770

Funding

SWG 2: Cure Research Scientific Working GroupP30AI117970 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI Italo Mocchetti · 2015 to 2026
$29.6M
Valacyclovir Phase I TrialU54AI150225 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MUGAVERO, MICHAEL J · 2019 to 2024
$7.6M
Mechanisms regulating poxvirus post-replicative protein synthesisR01AI143709 · NIAID · TEXAS A&M AGRILIFE RESEARCH · PI YANG, ZHILONG · 2019 to 2023
$1.9M
Poxvirus-encoded noncanonical open reading framesR21AI178638 · NIAID · TEXAS A&M AGRILIFE RESEARCH · PI YANG, ZHILONG · 2023 to 2024
$405k
NIAID NIH HHS P30 AI117970NIAID NIH HHS R01 AI143709NIAID NIH HHS R21 AI178638NIAID NIH HHS U54 AI150225NIH grants R01AI143709 and R21178638 BML was supported by the William L. Roberts Memorial Fund (553-Liu-11.20.20 and 553- 398 Mehta-08.31.20), ARUP Institute for Experimental Pathology. This publication resulted, in part, 399 from research supported by the District of Columbia Center for AID
6 · The paper itself

Abstract

Epidemiologic studies have established that mpox (formerly known as monkeypox) outbreaks worldwide in 2022-2023, due to Clade IIb mpox virus (MPXV), disproportionately affected gay, bisexual, and other men who have sex with men. More than 35% and 40% of the mpox cases suffer from co-infection with HIV and sexually transmitted infections (STIs) (e.g.,

Indexed as

CoinfectionHIV InfectionsSexually Transmitted DiseasesFemaleHumansMaleMonkeypox virusMpox, MonkeypoxSuperinfectionbacterial superinfectionco-infectiondiagnosisHIVmonkeypox virusmpoxorthopoxvirussexually transmitted infectiontrained immunitytreatment

Identifiers

PMID38793665
PMCPMC11125633

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.