Evidence map›Paper›PMID 38793660›Full record

ArticleViruses2024

Retrospective Analysis of Clinical Characteristics and Disease Outcomes in Children and Adolescents Hospitalized Due to COVID-19 Infection in Tunisia.

Aida Borgi, Khaoula Meftah, Ines Trabelsi, Moe H Kyaw, Hela Zaghden, Aida Bouafsoun, Fatma Mezghani, Nada Missaoui, Alya Abdel Ali, Leila Essaddam and 9 more

Abstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Aida BorgiPediatric Intensive Care Unit, Children's Hospital of Tunis, Tunis 1007, Tunisia.ORCID 0000-0003-2993-9209
Khaoula MeftahLaboratory of Microbiology, Children's Hospital of Tunis, Tunis 1007, Tunisia.ORCID 0000-0003-3312-8265
Ines TrabelsiPediatric Department B, Children's Hospital of Tunis, Tunis 1007, Tunisia.
Moe H KyawPfizer Inc., New York, NY 10017, USA.ORCID 0000-0002-0258-6645
Hela ZaghdenPfizer Inc., Tunis 1007, Tunisia.
Aida BouafsounLaboratory of Microbiology, Children's Hospital of Tunis, Tunis 1007, Tunisia.
Fatma MezghaniPediatric Department A, Children's Hospital of Tunis, Tunis 1007, Tunisia.
Nada MissaouiPediatric Department C, Children's Hospital of Tunis, Tunis 1007, Tunisia.ORCID 0000-0003-4317-5479
Alya Abdel AliDepartment of Pediatrics and Emergency, Children's Hospital of Tunis, Tunis 1007, Tunisia.
Leila EssaddamDepartment of Pediatrics and Emergency, Children's Hospital of Tunis, Tunis 1007, Tunisia.
Haifa KhemiriLaboratory of Clinical Virology, WHO Regional Reference Laboratory for Poliomyelitis and Measles for the EMR, Institute Pasteur of Tunis, Tunis 1002, Tunisia.
Sondes Haddad-BoubakerLaboratory of Clinical Virology, WHO Regional Reference Laboratory for Poliomyelitis and Measles for the EMR, Institute Pasteur of Tunis, Tunis 1002, Tunisia.ORCID 0000-0001-9705-4387
Khedija BoussettaPediatric Department B, Children's Hospital of Tunis, Tunis 1007, Tunisia.
Monia KhemiriPediatric Department A, Children's Hospital of Tunis, Tunis 1007, Tunisia.
Saida Ben BecherDepartment of Pediatrics and Emergency, Children's Hospital of Tunis, Tunis 1007, Tunisia.
Samir BoukthirPediatric Department C, Children's Hospital of Tunis, Tunis 1007, Tunisia.
Henda TrikiLaboratory of Clinical Virology, WHO Regional Reference Laboratory for Poliomyelitis and Measles for the EMR, Institute Pasteur of Tunis, Tunis 1002, Tunisia.
Khaled MenifPediatric Intensive Care Unit, Children's Hospital of Tunis, Tunis 1007, Tunisia.
Hanen SmaouiLaboratory of Microbiology, Children's Hospital of Tunis, Tunis 1007, Tunisia.ORCID 0000-0002-4026-0259

Funding

Pfizer Not applicable
6 · The paper itself

Abstract

Due to low susceptibility of coronavirus disease of 2019 (COVID-19) in children, limited studies are available regarding COVID-19 in the pediatric population in Tunisia. The current study evaluated the incidence, clinical characteristics, and outcomes of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) infection among children hospitalized at Béchir Hamza Children's Hospital. A retrospective cohort analysis was conducted using the hospital database between March 2020 and February 2022 with children aged ≤15 years with SARS-CoV-2 infection (confirmed by RT-PCR). A total of 327 COVID-19 hospitalized patients with a mean age of 3.3 years were included; the majority were male. Neurological disease (20%) was the most common comorbidity, while fever (95.3%) followed by cough (43.7%) and dyspnea (39.6%) were the most frequent symptoms reported. Severe disease with oxygen requirement occurred in 30% of the patients; 13% were admitted in the Intensive Care Unit. The overall incidence rate of COVID-19 hospitalization (in Tunis governorates) was 77.02 per 100,000 while the inpatient case fatality rate was 5% in the study population. The most prevalent circulating variant during our study period was Delta (48.8%), followed by Omicron (26%). More than 45% of the study population were <6 months and one-fourth (

Indexed as

ComorbidityCOVID-19HospitalizationSARS-CoV-2AdolescentChildChild, PreschoolFemaleHumansIncidenceInfantInfant, NewbornMaleRetrospective StudiesTunisiaclinical characteristicscomorbiditiesCOVID-19disease severityobservational studypediatric populationstudy outcomes

Identifiers

PMID38793660
PMCPMC11125722

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.