Evidence map›Paper›PMID 38793643›Full record

ArticleViruses2024

Genetic Characterization of Lumpy Skin Disease Viruses Circulating in Lesotho Cattle.

Mabusetsa Joseph Raporoto Makalo, Tirumala Bharani Kumar Settypalli, Irene Kasindi Meki, Mame Thierno Bakhoum, Hatem Ouled Ahmed, Moeketsi Solomon Phalatsi, Tsepo Ramatla, ThankGod Emmanuel Onyiche, Lineo Nionzima-Bohloa, Artem Metlin and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mabusetsa Joseph Raporoto MakaloUnit for Environmental Sciences and Management, North-West University, Potchefstroom 2531, South Africa.ORCID 0000-0001-7388-698X
Tirumala Bharani Kumar SettypalliAnimal Production and Health Laboratory, Animal Production and Health Section, Joint FAO/IAEA Division, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, P.O. Box 100, 1400 Vienna, Austria.ORCID 0000-0002-9090-8471
Irene Kasindi MekiAnimal Production and Health Laboratory, Animal Production and Health Section, Joint FAO/IAEA Division, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, P.O. Box 100, 1400 Vienna, Austria.ORCID 0000-0001-5983-2088
Mame Thierno BakhoumLaboratoire National de l'Elevage et de Recherches Vétérinaires ISRA/LNERV(LNERV), BP 2057, Dakar, Senegal.ORCID 0000-0001-6794-4426
Hatem Ouled AhmedAnimal Production and Health Laboratory, Animal Production and Health Section, Joint FAO/IAEA Division, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, P.O. Box 100, 1400 Vienna, Austria.
Moeketsi Solomon PhalatsiDepartment of Animal Science, National University of Lesotho, P.O. Roma 180, Lesotho.
Tsepo RamatlaUnit for Environmental Sciences and Management, North-West University, Potchefstroom 2531, South Africa.
ThankGod Emmanuel OnyicheUnit for Environmental Sciences and Management, North-West University, Potchefstroom 2531, South Africa.ORCID 0000-0001-6738-2291
Lineo Nionzima-BohloaDepartment of Livestock Services, Ministry of Agriculture, Food Security, and Nutrition, Private A82, Maseru, Lesotho.
Artem MetlinFood and Agriculture Organization of the United Nations, Viale delle Terme di Caracalla, 00153 Rome, Italy.ORCID 0000-0002-4283-0171
Madhur DhingraFood and Agriculture Organization of the United Nations, Viale delle Terme di Caracalla, 00153 Rome, Italy.
Giovanni CattoliAnimal Production and Health Laboratory, Animal Production and Health Section, Joint FAO/IAEA Division, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, P.O. Box 100, 1400 Vienna, Austria.
Charles Euloge LamienAnimal Production and Health Laboratory, Animal Production and Health Section, Joint FAO/IAEA Division, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, P.O. Box 100, 1400 Vienna, Austria.ORCID 0000-0003-1899-7614
Oriel Matlhahane Molifi ThekisoeUnit for Environmental Sciences and Management, North-West University, Potchefstroom 2531, South Africa.ORCID 0000-0003-0700-4787

Funding

International Atomic Energy Agency EVT2205957, RAF5082, LES5010 and LES5011National Research Foundation (NRF) Incentive Funding for Rated Researchers GUN94187 and GUN118949
6 · The paper itself

Abstract

Lumpy skin disease is one of the fast-spreading viral diseases of cattle and buffalo that can potentially cause severe economic impact. Lesotho experienced LSD for the first time in 1947 and episodes of outbreaks occurred throughout the decades. In this study, eighteen specimens were collected from LSD-clinically diseased cattle between 2020 and 2022 from Mafeteng, Leribe, Maseru, Berea, and Mohales' Hoek districts of Lesotho. A total of 11 DNA samples were analyzed by PCR and sequencing of the extracellular enveloped virus (EEV) glycoprotein, G-protein-coupled chemokine receptor (GPCR), 30 kDa RNA polymerase subunit (RPO30), and B22R genes. All nucleotide sequences of the above-mentioned genes confirmed that the PCR amplicons of clinical samples are truly LSDV, as they were identical to respective LSDV isolates on the NCBI GenBank. Two of the elevem samples were further characterized by whole-genome sequencing. The analysis, based on both CaPV marker genes and complete genome sequences, revealed that the LSDV isolates from Lesotho cluster with the NW-like LSDVs, which includes the commonly circulating LSDV field isolates from Africa, the Middle East, the Balkans, Turkey, and Eastern Europe.

Indexed as

Lumpy Skin DiseaseLumpy skin disease virusPhylogenyAnimalsCattleGenome, ViralLesothoWhole Genome SequencingcattleLesotholumpy skin disease viruswhole genome

Identifiers

PMID38793643
PMCPMC11125814

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.