Evidence map›Paper›PMID 38793604›Full record

ArticleViruses2024

Gut Microbiome and Cytokine Profiles in Post-COVID Syndrome.

Karakoz Mussabay, Samat Kozhakhmetov, Marat Dusmagambetov, Aitolkyn Mynzhanova, Madiyar Nurgaziyev, Zharkyn Jarmukhanov, Elizaveta Vinogradova, Aigul Dusmagambetova, Aiganym Daulbaeva, Laura Chulenbayeva and 3 more

Abstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Comparative urinary metabolomics reveals unique and shared pathways in COVID-19 and liver diseases.Metabolomics : Official journal of the Metabolomic Society · 2026
    Article
  3. Review
  4. Review
  5. Microbiome and Long COVID-19: Current Evidence and Insights.International journal of molecular sciences · 2025
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Karakoz MussabayDepartment of Microbiology and Virology Named after Sh.I.Sarbasova, Astana Medical University, Astana 010000, Kazakhstan.ORCID 0000-0001-7440-4014
Samat KozhakhmetovLaboratory of Microbiome, Center for Life Sciences, National Laboratory Astana, Nazarbayev University, Astana 010000, Kazakhstan.ORCID 0000-0001-9668-0327
Marat DusmagambetovDepartment of Microbiology and Virology Named after Sh.I.Sarbasova, Astana Medical University, Astana 010000, Kazakhstan.ORCID 0000-0003-2395-6032
Aitolkyn MynzhanovaDepartment of Pediatric Infectious Diseases, Astana Medical University, Astana 010000, Kazakhstan.
Madiyar NurgaziyevLaboratory of Microbiome, Center for Life Sciences, National Laboratory Astana, Nazarbayev University, Astana 010000, Kazakhstan.
Zharkyn JarmukhanovLaboratory of Microbiome, Center for Life Sciences, National Laboratory Astana, Nazarbayev University, Astana 010000, Kazakhstan.
Elizaveta VinogradovaLaboratory of Microbiome, Center for Life Sciences, National Laboratory Astana, Nazarbayev University, Astana 010000, Kazakhstan.ORCID 0009-0003-1845-2726
Aigul DusmagambetovaDepartment of Microbiology and Virology Named after Sh.I.Sarbasova, Astana Medical University, Astana 010000, Kazakhstan.
Aiganym DaulbaevaDepartment of Pediatric Infectious Diseases, Astana Medical University, Astana 010000, Kazakhstan.
Laura ChulenbayevaLaboratory of Microbiome, Center for Life Sciences, National Laboratory Astana, Nazarbayev University, Astana 010000, Kazakhstan.
Ainur TauekelovaNational Research Cardiac Surgery Center, Astana 010000, Kazakhstan.
Makhabbat BekbossynovaNational Research Cardiac Surgery Center, Astana 010000, Kazakhstan.
Almagul KushugulovaLaboratory of Microbiome, Center for Life Sciences, National Laboratory Astana, Nazarbayev University, Astana 010000, Kazakhstan.ORCID 0000-0001-9479-0899

Funding

Committee of Science of the Ministry of Science and Higher Education of the Republic of Kazakhstan BR21882152
6 · The paper itself

Abstract

Recent studies highlight the crucial role of the gut microbiome in post-infectious complications, especially in patients recovering from severe COVID-19. Our research aimed to explore the connection between gut microbiome changes and the cytokine profile of patients with post-COVID syndrome. Using 16S rRNA amplicon sequencing, we analyzed the composition of the gut microbiome in 60 COVID-19 patients over the course of one year. We also measured the levels of serum cytokines and chemokines using the Milliplex system. Our results showed that severe SARS-CoV-2 infection cases, especially those complicated by pneumonia, induce a pro-inflammatory microbial milieu with heightened presence of

Indexed as

COVID-19CytokinesGastrointestinal MicrobiomeSARS-CoV-2AdultAgedFecesFemaleHumansMaleMiddle AgedPost-Acute COVID-19 SyndromeRNA, Ribosomal, 16SCytokinesRNA, Ribosomal, 16Scytokinescytokine stormgut microbiomePost-COVIDSARS-CoV-2

Identifiers

PMID38793604
PMCPMC11126011

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.