Evidence map›Paper›PMID 38793603›Full record

ArticleViruses2024

Epigenetic Modifications of White Blood Cell DNA Caused by Transient Fetal Infection with Bovine Viral Diarrhea Virus.

Hana Van Campen, Jeanette V Bishop, Zella Brink, Terry E Engle, Carolina L Gonzalez-Berrios, Hanah M Georges, Jessica N Kincade, Dilyara A Murtazina, Thomas R Hansen

Abstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hana Van CampenDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.ORCID 0000-0003-3100-9174
Jeanette V BishopDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Zella BrinkDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Terry E EngleDepartment of Animal Science, Colorado State University, Fort Collins, CO 80523, USA.
Carolina L Gonzalez-BerriosDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.ORCID 0000-0003-2068-5046
Hanah M GeorgesDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.ORCID 0000-0001-9065-9885
Jessica N KincadeDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Dilyara A MurtazinaDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Thomas R HansenDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.

Funding

United States Department of Agriculture NIFA-AFRI 2019-67015-29866United States Department of Agriculture NIFA Hatch/Multi State Research Accession No. 1011648, W114 Project No. COLO0220C
6 · The paper itself

Abstract

Bovine viral diarrhea virus (BVDV) infections cause USD 1.5-2 billion in losses annually. Maternal BVDV after 150 days of gestation causes transient fetal infection (TI) in which the fetal immune response clears the virus. The impact of fetal TI BVDV infections on postnatal growth and white blood cell (WBC) methylome as an index of epigenetic modifications was examined by inoculating pregnant heifers with noncytopathic type 2 BVDV or media (sham-inoculated controls) on Day 175 of gestation to generate TI (

Indexed as

Bovine Virus Diarrhea-Mucosal DiseaseDiarrhea Viruses, Bovine ViralDNA MethylationEpigenesis, GeneticLeukocytesAnimalsAntibodies, ViralCattleDiarrhea Virus 2, Bovine ViralFemaleFetal DiseasesFetusPregnancyAntibodies, Viralbovine viral diarrhea virusepigeneticsimmune systemintrauterine growth restrictionpathway analysistransient infection

Identifiers

PMID38793603
PMCPMC11125956

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.