Evidence map›Paper›PMID 38793563›Full record

ArticleViruses2024

Monkeypox Virus Neutralizing Antibodies at Six Months from Mpox Infection: Virologic Factors Associated with Poor Immunologic Response.

Angelo Roberto Raccagni, Alessandro Mancon, Sara Diotallevi, Riccardo Lolatto, Elena Bruzzesi, Maria Rita Gismondo, Antonella Castagna, Davide Mileto, Silvia Nozza

Abstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Angelo Roberto RaccagniInfectious Diseases Unit, Vita-Salute San Raffaele University, 20132 Milan, Italy.ORCID 0000-0001-7811-6255
Alessandro ManconLaboratory of Clinical Microbiology, Virology and Bioemergencies, Ospedale Sacco, 20157 Milan, Italy.ORCID 0000-0002-1490-636X
Sara DiotalleviInfectious Diseases Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.ORCID 0009-0003-2559-7042
Riccardo LolattoInfectious Diseases Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.ORCID 0000-0002-2447-6498
Elena BruzzesiInfectious Diseases Unit, Vita-Salute San Raffaele University, 20132 Milan, Italy.
Maria Rita GismondoLaboratory of Clinical Microbiology, Virology and Bioemergencies, Ospedale Sacco, 20157 Milan, Italy.
Antonella CastagnaInfectious Diseases Unit, Vita-Salute San Raffaele University, 20132 Milan, Italy.
Davide MiletoLaboratory of Clinical Microbiology, Virology and Bioemergencies, Ospedale Sacco, 20157 Milan, Italy.ORCID 0000-0002-9414-0287
Silvia NozzaInfectious Diseases Unit, Vita-Salute San Raffaele University, 20132 Milan, Italy.ORCID 0000-0002-2673-2731

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A natural monkeypox virus infection may not induce sufficient neutralizing antibody responses in a subset of healthy individuals. The aim of this study was to evaluate monkeypox virus-neutralizing antibodies six months after infection and to assess the virological factors predictive of a poor immunological response. Antibodies were assessed using a plaque reduction neutralization test at six months from mpox infection; mpox cutaneous, oropharyngeal, and anal swabs, semen, and plasma samples were tested during infection. Overall, 95 people were included in the study; all developed detectable antibodies. People who were positive for the monkeypox virus for more days had higher levels of antibodies when considering all tested samples (

Indexed as

Antibodies, NeutralizingAntibodies, ViralMonkeypox virusMpox, MonkeypoxNeutralization TestsViral LoadAdultFemaleHumansMaleMiddle AgedYoung AdultAntibodies, NeutralizingAntibodies, Viralimmunitymonkeypoxmpoxneutralizing antibodiesserology

Identifiers

PMID38793563
PMCPMC11125824

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.