Evidence map›Paper›PMID 38793537›Full record

ArticleViruses2024

Impact of the COVID-19 Pandemic on Hepatitis C Treatment Initiation in British Columbia, Canada: An Interrupted Time Series Study.

Richard L Morrow, Mawuena Binka, Julia Li, Mike Irvine, Sofia R Bartlett, Stanley Wong, Dahn Jeong, Jean Damascene Makuza, Jason Wong, Amanda Yu and 2 more

Abstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Richard L MorrowBritish Columbia Centre for Disease Control, Vancouver, BC V5Z 4R4, Canada.ORCID 0000-0002-5869-5197
Mawuena BinkaBritish Columbia Centre for Disease Control, Vancouver, BC V5Z 4R4, Canada.
Julia LiBritish Columbia Centre for Disease Control, Vancouver, BC V5Z 4R4, Canada.
Mike IrvineBritish Columbia Centre for Disease Control, Vancouver, BC V5Z 4R4, Canada.
Sofia R BartlettBritish Columbia Centre for Disease Control, Vancouver, BC V5Z 4R4, Canada.ORCID 0000-0003-0699-2250
Stanley WongBritish Columbia Centre for Disease Control, Vancouver, BC V5Z 4R4, Canada.
Dahn JeongBritish Columbia Centre for Disease Control, Vancouver, BC V5Z 4R4, Canada.ORCID 0000-0003-1782-5669
Jean Damascene MakuzaBritish Columbia Centre for Disease Control, Vancouver, BC V5Z 4R4, Canada.ORCID 0000-0001-9275-8844
Jason WongBritish Columbia Centre for Disease Control, Vancouver, BC V5Z 4R4, Canada.
Amanda YuBritish Columbia Centre for Disease Control, Vancouver, BC V5Z 4R4, Canada.
Mel KrajdenBritish Columbia Centre for Disease Control, Vancouver, BC V5Z 4R4, Canada.
Naveed Zafar JanjuaBritish Columbia Centre for Disease Control, Vancouver, BC V5Z 4R4, Canada.ORCID 0000-0001-5681-719X

Funding

CIHR WI1-179874
6 · The paper itself

Abstract

We investigated the impacts of the COVID-19 pandemic on hepatitis C (HCV) treatment initiation, including by birth cohort and injection drug use status, in British Columbia (BC), Canada. Using population data from the BC COVID-19 Cohort, we conducted interrupted time series analyses, estimating changes in HCV treatment initiation following the introduction of pandemic-related policies in March 2020. The study included a pre-policy period (April 2018 to March 2020) and three follow-up periods (April to December 2020, January to December 2021, and January to December 2022). The level of HCV treatment initiation decreased by 26% in April 2020 (rate ratio 0.74, 95% confidence interval [CI] 0.60 to 0.91). Overall, no statistically significant difference in HCV treatment initiation occurred over the 2020 and 2021 post-policy periods, and an increase of 34.4% (95% CI 0.6 to 75.8) occurred in 2022 (equating to 321 additional people initiating treatment), relative to expectation. Decreases in HCV treatment initiation occurred in 2020 for people born between 1965 and 1974 (25.5%) and people who inject drugs (24.5%), relative to expectation. In summary, the pandemic was associated with short-term disruptions in HCV treatment initiation in BC, which were greater for people born 1965 to 1974 and people who inject drugs.

Indexed as

Antiviral AgentsCOVID-19Hepatitis CInterrupted Time Series AnalysisAdultAgedBritish ColumbiaCohort StudiesFemaleHumansMaleMiddle AgedPandemicsSARS-CoV-2Substance Abuse, IntravenousAntiviral AgentsBritish ColumbiacascadeCOVID-19hepatitis Cinterrupted time series analysis

Identifiers

PMID38793537
PMCPMC11125629

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.